关键词: Cervical cancer Double J stent Nephrostomy Obstructive uropathy Predictors

来  源:   DOI:10.14740/wjon1631   PDF(Pubmed)

Abstract:
UNASSIGNED: Cervical cancer remains the most lethal and prevalent cancer among women. Obstructive uropathy is a common complication of advanced cervical cancer, caused by the expanding tumor. One of the recommended treatments for this condition is the implantation of a double J (DJ) stent. However, this procedure is challenging due to the unique characteristics of the patient. The objective of this study was to identify the variables that influence the successful insertion of a DJ stent in women with advanced cervical cancer.
UNASSIGNED: This retrospective study included women who attempted to have a DJ stent implanted at the General Hospital of Adam Malik in Medan, Indonesia, between January 2020 and December 2022, and were diagnosed with advanced cervical cancer. The inclusion criteria were limited to cervical cancer patients in stages III-IV, according to the International Federation of Gynecology and Obstetrics (FIGO) staging standard, who underwent an attempt at DJ stent insertion. Patients who underwent a nephrostomy and received a DJ stent were excluded from the study. The participants were divided into two groups based on the success of the DJ stent implantation. The analysis was conducted using the logistic regression test and the Chi-square test.
UNASSIGNED: The study included 88 patients with advanced-stage cervical cancer, of whom 45 underwent nephrostomy and 43 received a DJ stent. The analysis revealed that lower levels of hydronephrosis (odds ratio (OR): 18.203, P = 0.001), urea (OR: 4.207, P = 0.037), and creatinine (OR: 6.923, P = 0.004), higher levels of urine output (OR: 8.26, P = 0.003), and lower cervical cancer stage (OR: 4.125, P = 0.022) were all predictors of successful DJ stent insertion.
UNASSIGNED: For women with advanced cervical cancer, lower degrees of hydronephrosis, urea, and creatinine levels, higher urine output, and lower cervical cancer stage were all predictive factors for successful DJ stent implantation.
摘要:
宫颈癌仍然是女性中最致命和最普遍的癌症。梗阻性尿路病是晚期宫颈癌的常见并发症,由不断扩大的肿瘤引起的。这种情况的推荐治疗方法之一是植入双J(DJ)支架。然而,由于患者的独特特征,该程序具有挑战性。这项研究的目的是确定影响晚期宫颈癌女性成功插入DJ支架的变量。
这项回顾性研究包括试图在棉兰的亚当·马利克总医院植入DJ支架的女性,印度尼西亚,在2020年1月至2022年12月期间,被诊断为晚期宫颈癌。纳入标准仅限于III-IV期宫颈癌患者,根据国际妇产科联合会(FIGO)分期标准,尝试插入DJ支架的人。接受肾造口术并接受DJ支架的患者被排除在研究之外。根据DJ支架植入的成功将参与者分为两组。采用logistic回归检验和卡方检验进行分析。
该研究包括88例晚期宫颈癌患者,其中45人接受了肾造口术,43人接受了DJ支架。分析显示肾积水水平较低(比值比(OR):18.203,P=0.001),尿素(OR:4.207,P=0.037),和肌酐(OR:6.923,P=0.004),尿量水平较高(OR:8.26,P=0.003),和较低的宫颈癌分期(OR:4.125,P=0.022)都是成功插入DJ支架的预测因素。
对于患有晚期宫颈癌的女性,肾积水程度较低,尿素,和肌酐水平,尿量增加,和较低的宫颈癌分期都是成功植入DJ支架的预测因素。
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