关键词: COVID-19 Cases epidemiology outbreak variant

Mesh : Humans COVID-19 / epidemiology Pandemics Malaysia / epidemiology Disease Outbreaks Hospitalization

来  源:   DOI:10.3389/fpubh.2024.1289622   PDF(Pubmed)

Abstract:
Since the COVID-19 pandemic began, it has spread rapidly across the world and has resulted in recurrent outbreaks. This study aims to describe the COVID-19 epidemiology in terms of COVID-19 cases, deaths, ICU admissions, ventilator requirements, testing, incidence rate, death rate, case fatality rate (CFR) and test positivity rate for each outbreak from the beginning of the pandemic in 2020 till endemicity of COVID-19 in 2022 in Malaysia.
Data was sourced from the GitHub repository and the Ministry of Health\'s official COVID-19 website. The study period was from the beginning of the outbreak in Malaysia, which began during Epidemiological Week (Ep Wk) 4 in 2020, to the last Ep Wk 18 in 2022. Data were aggregated by Ep Wk and analyzed in terms of COVID-19 cases, deaths, ICU admissions, ventilator requirements, testing, incidence rate, death rate, case fatality rate (CFR) and test positivity rate by years (2020 and 2022) and for each outbreak of COVID-19.
A total of 4,456,736 cases, 35,579 deaths and 58,906,954 COVID-19 tests were reported for the period from 2020 to 2022. The COVID-19 incidence rate, death rate, CFR and test positivity rate were reported at 1.085 and 0.009 per 1,000 populations, 0.80 and 7.57%, respectively, for the period from 2020 to 2022. Higher cases, deaths, testing, incidence/death rate, CFR and test positivity rates were reported in 2021 and during the Delta outbreak. This is evident by the highest number of COVID-19 cases, ICU admissions, ventilatory requirements and deaths observed during the Delta outbreak.
The Delta outbreak was the most severe compared to other outbreaks in Malaysia\'s study period. In addition, this study provides evidence that outbreaks of COVID-19, which are caused by highly virulent and transmissible variants, tend to be more severe and devastating if these outbreaks are not controlled early on. Therefore, close monitoring of key epidemiological indicators, as reported in this study, is essential in the control and management of future COVID-19 outbreaks in Malaysia.
摘要:
自从COVID-19大流行开始以来,它在世界各地迅速蔓延,并导致反复爆发。这项研究旨在从COVID-19病例的角度描述COVID-19的流行病学,死亡,ICU入院,呼吸机要求,测试,发病率,死亡率,从2020年大流行开始到2022年COVID-19在马来西亚流行的每次疫情的病死率(CFR)和测试阳性率。
数据来自GitHub存储库和卫生部官方COVID-19网站。研究期间是从马来西亚爆发疫情开始,从2020年的流行病学周(EpWk)4开始,到2022年的最后一个EpWk18。数据按EpWK汇总,并根据COVID-19病例进行分析,死亡,ICU入院,呼吸机要求,测试,发病率,死亡率,按年份(2020年和2022年)和每次COVID-19爆发的病死率(CFR)和检测阳性率。
共4,456,736例,在2020年至2022年期间,报告了35579例死亡和58906954例COVID-19检测。COVID-19的发病率,死亡率,CFR和测试阳性率分别为1.085和0.009/1000人口,0.80和7.57%,分别,2020年至2022年期间。更高的案例,死亡,测试,发病率/死亡率,在2021年和三角洲疫情期间报告了CFR和测试阳性率。COVID-19病例数量最多,这一点很明显,ICU入院,在三角洲疫情期间观察到的通气需求和死亡。
与马来西亚研究期间的其他疫情相比,三角洲疫情是最严重的。此外,这项研究提供了证据表明,由高毒力和传染性变种引起的COVID-19爆发,如果这些疫情没有得到早期控制,往往会更加严重和具有破坏性。因此,密切监测关键流行病学指标,正如这项研究报告的那样,对于马来西亚未来COVID-19疫情的控制和管理至关重要。
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