Abstract：
Multi-systemic metastasis in patients with Peutz-Jeghers syndrome (PJS) is very rare, and there are nearly no relevant imaging reports, especially in contrast-enhanced ultrasound (CEUS). We present here a 40-year-old male patient who underwent several partial small bowel resections and endoscopic polypectomy for intestinal polyps. After reviewing the patient\'s clinical diagnosis and treatment process, CEUS with sulfur hexafluoride microbubbles (SonoVue, Bracco, Milan, Italy) in the liver and gastrointestinal tract was performed. We imaged multiple abnormal masses with sonographic features consistent with malignancies. Combined with other imaging examinations and 18 gauge core-needle puncture biopsy of liver masses, multiple metastases outside the gastrointestinal tract were considered. This case report suggests CEUS may be an easy, effective, and supplementary method for evaluating PJS patients with suspected multi-systemic malignant lesions including the gastrointestinal tract.
摘要：
Peutz-Jeghers综合征（PJS）患者的多系统转移非常罕见，几乎没有相关的影像学报告，尤其是在超声造影（CEUS）。我们在这里介绍一名40岁的男性患者，他接受了几次小肠部分切除术和内镜下息肉切除术治疗肠息肉。在回顾患者的临床诊断和治疗过程后,含六氟化硫微泡的CEUS(SonoVue，Bracco,米兰,意大利）在肝脏和胃肠道进行。我们对多个异常肿块进行了成像，其超声特征与恶性肿瘤一致。结合其他影像学检查和18号针穿刺活检肝肿块，考虑到胃肠道外的多发转移.这份病例报告表明CEUS可能很容易，有效,以及评估怀疑包括胃肠道在内的多系统恶性病变的PJS患者的补充方法。
