PDF(Pubmed)
Abstract：
BACKGROUND: Radiotherapy (RT) plays an important role in the therapeutic management of vestibular schwannoma (VS). Fractionated stereotactic radiotherapy (FSRT) or radiosurgery (SRS) are the two modalities available. The purpose of this article is to review the results of VS RT studies carried out over the last ten years.
METHODS: A literature search was performed with PubMed and Medline by using the words vestibular schwannoma, acoustic neuroma, radiotherapy, and radiosurgery.
RESULTS: In small (<3 cm) VS, SRS offers a local control rate of >90%, which seems similar to microsurgery, with a favorable tolerance profile. Hypofractionated FSRT (three to five fractions) is a relatively recent modality and has shown similar outcomes to normofractionated FSRT. Hearing preservation may highly differ between studies, but it is around 65% at 5 years.
CONCLUSIONS: SRS and FRST are non-invasive treatment options for VS. SRS is often preferred for small lesions less than 3 cm, and FSRT for larger lesions. However, no randomized study has compared these modalities.
METHODS: A literature search was performed with PubMed and Medline by using the words vestibular schwannoma, acoustic neuroma, radiotherapy, and radiosurgery.
RESULTS: In small (<3 cm) VS, SRS offers a local control rate of >90%, which seems similar to microsurgery, with a favorable tolerance profile. Hypofractionated FSRT (three to five fractions) is a relatively recent modality and has shown similar outcomes to normofractionated FSRT. Hearing preservation may highly differ between studies, but it is around 65% at 5 years.
CONCLUSIONS: SRS and FRST are non-invasive treatment options for VS. SRS is often preferred for small lesions less than 3 cm, and FSRT for larger lesions. However, no randomized study has compared these modalities.
摘要：
背景：放射治疗（RT）在前庭神经鞘瘤（VS）的治疗管理中起着重要作用。分次立体定向放射治疗（FSRT）或放射外科（SRS）是两种可用的方式。本文的目的是回顾过去十年来进行的VSRT研究的结果。
方法：使用PubMed和Medline进行文献检索，使用前庭神经鞘瘤，听神经瘤,放射治疗,和放射外科。
结果：在小（<3厘米）VS中，SRS提供>90%的本地控制率，这看起来类似于显微外科手术，具有良好的公差轮廓。低分割FSRT（三到五个部分）是一种相对较新的模式，并且显示出与正常分割FSRT相似的结果。不同研究之间的听力保护可能有很大的不同，但5年时约为65%。
结论：SRS和FRST是VS的非侵入性治疗选择。对于小于3厘米的小病灶，SRS通常是首选。和FSRT用于较大病变。然而,没有随机研究对这些模式进行比较.
方法：使用PubMed和Medline进行文献检索，使用前庭神经鞘瘤，听神经瘤,放射治疗,和放射外科。
结果：在小（<3厘米）VS中，SRS提供>90%的本地控制率，这看起来类似于显微外科手术，具有良好的公差轮廓。低分割FSRT（三到五个部分）是一种相对较新的模式，并且显示出与正常分割FSRT相似的结果。不同研究之间的听力保护可能有很大的不同，但5年时约为65%。
结论：SRS和FRST是VS的非侵入性治疗选择。对于小于3厘米的小病灶，SRS通常是首选。和FSRT用于较大病变。然而,没有随机研究对这些模式进行比较.
