PDF(Pubmed)
Abstract：
Peri-implant diseases including peri-implant mucositis and peri-implantitis are among the major causes of failure of implant-supported dental restorations. They are characterized by progressive inflammation of the peri-implant mucosa, extending to the surrounding connective tissues and leading to bone loss and implant failure. Although strict oral hygiene practices help in preventing peri-implant diseases, plaque buildup around the implant restoration leads to chronic inflammation, due to the adherent bacterial biofilm. While mechanical debridement and non-surgical therapy to remove inflamed connective tissue (ICT) form the mainstay of treatment, additional local adjunctive therapies enhance clinical outcomes. Topical oxygen therapy is known to reduce inflammation, increase vascularity, and act as a bacteriostatic measure. The use of oxygen-based therapy (blue®m) products as a local adjunctive therapy for peri-implant mucositis and peri-implantitis can result in clinical outcomes similar to that of conventional local adjuncts such as chlorhexidine, antibiotics, and antibacterial agents. This report aims to present the clinical findings of patients with peri-implant mucositis and peri-implantitis, who were managed using local oxygen-based therapy as an adjunct to non-surgical therapy. In addition, a review of the literature about commonly used local adjuncts for peri-implant diseases has been included in the report to provide a means of comparison between conventional local adjunct therapy and topical oxygen-based therapy. Based on the reported findings and reviewed literature, local oxygen-based adjunct therapy was equally effective as conventionally used local adjuncts such as antibiotics, antibacterials, and probiotics, in treating patients with peri-implant diseases.
摘要：
包括种植体周围粘膜炎和种植体周围炎在内的种植体周围疾病是种植体支持的牙科修复体失败的主要原因。它们的特征是种植体周围粘膜进行性炎症，延伸到周围的结缔组织，导致骨丢失和植入物失败。尽管严格的口腔卫生习惯有助于预防种植体周围疾病，植入物修复周围的斑块积聚导致慢性炎症，由于粘附的细菌生物膜。虽然机械清创术和非手术治疗以去除发炎的结缔组织（ICT）是治疗的主要手段，额外的局部辅助治疗可提高临床结局.已知局部氧疗可以减少炎症，增加血管，作为一种抑菌措施。使用基于氧的治疗（blue®m）产品作为种植体周围黏膜炎和种植体周围炎的局部辅助治疗可导致与传统局部辅助治疗如氯己定相似的临床结果。抗生素,和抗菌剂。本报告旨在介绍种植体周围黏膜炎和种植体周围炎患者的临床发现，使用局部氧基治疗作为非手术治疗的辅助治疗。此外,本报告对种植体周围疾病常用局部辅助治疗的文献进行了综述,以提供常规局部辅助治疗和局部氧疗的比较方法.根据报告的发现和文献综述，局部氧基辅助治疗与常规使用的抗生素等局部辅助治疗同样有效，抗菌药物,和益生菌，治疗种植体周围疾病的患者。
