PDF(Pubmed)
Abstract：
Healthcare visits were reduced during the COVID-19 pandemic, causing disturbances in sustainable MAFLD monitoring. Telemedicine acts to maintain connectivity between patients and healthcare professionals. This review aimed to assess the role of telemedicine in monitoring MAFLD during the pandemic. Databases searched included l PubMed Central and ScienceDirect from 2020 to 2023. Assessment with The Cochrane Risk of Bias for randomized controlled trials (RCTs) and the Newcastle-Ottawa scale for non-RCTs systematic reviews. Meta-analyses employing a random-effect model were performed to determine the pooled mean difference (MD) and p-value. The results showed three RCT and two non-RCT (n = 239) with 56.9% males and a mean age of 51.3 years. The median intervention duration was 5.5 months. The parameters assessed included body weight (BW), body mass index (BMI), waist circumference, liver function (AST/ALT), lipid profile, HbA1c, and others. Meta-analysis revealed that telemedicine had a significant effect on improving outcomes for BW (MD -2.81: 95% CI, -4.11, -1.51, p < 0.0001) and BMI (MD -1.01: 95% CI, -1.47, -0.55, p < 0.0001) compared to standard care, while the AST/ALT levels were not significantly reduced. Some biochemical markers decreased based on the systematic reviews. In conclusion, telemedicine using mobile-based applications could be an option for monitoring lifestyle modification in MAFLD patients facing the COVID-19 pandemic.
摘要：
在COVID-19大流行期间，医疗保健访问减少了，在可持续的MAFLD监测中造成干扰。远程医疗的作用是保持患者和医疗保健专业人员之间的连通性。这篇综述旨在评估远程医疗在大流行期间监测MAFLD的作用。搜索的数据库包括2020年至2023年的lPubMedCentral和ScienceDirect。随机对照试验(RCTs)的Cochrane偏差风险评估和非RCTs系统评价的纽卡斯尔-渥太华量表。使用随机效应模型进行荟萃分析以确定合并平均差（MD）和p值。结果显示三个RCT和两个非RCT（n=239），男性占56.9％，平均年龄为51.3岁。中位干预时间为5.5个月。评估的参数包括体重(BW)，体重指数（BMI），腰围,肝功能（AST/ALT），血脂谱,HbA1c,和其他人。荟萃分析显示，远程医疗对改善BW（MD-2.81：95％CI，-4.11，-1.51，p<0.0001）和BMI（MD-1.01：95％CI，-1.47，-0.55，p<0.0001）的结果具有显着效果。而AST/ALT水平没有显着降低。根据系统评价，一些生化标志物下降。总之,使用基于移动的应用程序的远程医疗可能是监测面临COVID-19大流行的MAFLD患者生活方式改变的一种选择。
