PDF(Pubmed)
Abstract：
Craniopharyngioma (CP) treatment, including surgery and radiotherapy, can have short- and long-term vascular side effects. Hypothalamic damage is related to morbid obesity and may increase the lifelong risk of experiencing vascular events in CP patients. This review summarized the available evidence regarding vascular complications in adamantinomatous or papillary CP patients, whatever their age at diagnosis. Three databases (Medline, CINAHL, Web of Science) were searched (06/2023) to retrieve eligible articles. The search was limited to peer-reviewed articles. Titles, abstracts, and full texts were screened by two independent reviewers, and data were extracted using a self-developed grid. Seventy-two studies were included in this review; the majority were case reports. Reported vascular sequela that occurred due to surgery were fusiform dilation of the carotid artery, stroke, vasospasm, hemorrhage, and aneurysm. Related conditions that emerged due to radiotherapy included Moyamoya syndrome and cavernoma. Cardiovascular morbidity and mortality often lead to hypothalamic obesity and metabolic syndrome in CP patients. Vascular damage is a rare complication of CP treatment. Surgical strategies should protect the surrounding hypothalamic and vascular structures. Patients receiving radiotherapy, particularly at a young age, should undergo magnetic resonance angiography monitoring to identify possible neurovascular sequela during post-treatment care.
摘要：
颅咽管瘤（CP）治疗，包括手术和放疗,可能有短期和长期的血管副作用。下丘脑损伤与病态肥胖有关，并可能增加CP患者经历血管事件的终身风险。这篇综述总结了有关金刚烷胺瘤或乳头状CP患者血管并发症的现有证据。无论他们在诊断时的年龄。三个数据库(Medline，CINAHL,WebofScience）进行了搜索（2023年6月）以检索符合条件的文章。搜索仅限于同行评审的文章。标题,摘要,全文由两名独立审稿人筛选，数据是使用自主开发的网格提取的。本综述包括72项研究；大多数是病例报告。手术引起的血管后遗症为颈动脉梭形扩张,中风,血管痉挛,出血,和动脉瘤。由于放疗而出现的相关疾病包括烟雾综合征和海绵状瘤。心血管疾病的发病率和死亡率通常会导致CP患者的下丘脑肥胖和代谢综合征。血管毁伤是CP医治的罕见并发症。手术策略应保护周围的下丘脑和血管结构。接受放疗的患者，尤其是在年轻的时候，在治疗后护理期间,应进行磁共振血管造影监测,以确定可能的神经血管后遗症.
