Abstract：
Background: Lactation induction in transgender women is a clinical and research priority in the field of breastfeeding medicine. To date, there are four case reports detailing successful induced lactation in transgender patients who wished to breastfeed. The Academy of Breast Feeding Medicine does not formally recommend a specific medication regimen for transgender patients due to lack of high-quality research. Case Presentation: A 50-year-old transgender woman with a hypercoagulable disorder who was able to lactate and breastfeed with novel hormone regimen management at a gender care clinic. Her baseline hormone treatment was an estradiol 0.3 mg transdermal patch every 72 hours and micronized progesterone 200 mg daily. Results: Within four weeks of initiating a modified hormone regimen (estradiol 0.4 mg patch every 72 hours, progesterone 300 mg daily, metoclopramide 10 mg three times daily), the patient was lactating spontaneously. On multiple occasions, she breastfed and expressed up to 30 mL of milk through pumping. Conclusion: This report offers a new effective hormone regimen for transgender patients who wish to lactate and cannot access domperidone-the galactagogue used in previous case reports. It also provides a review of previously published case reports on this subject. Future research in this field should prioritize cohort studies of transgender patients who desire lactation to further assess patient attitudes, experiences, and outcomes.
摘要：
背景：变性女性的泌乳诱导是母乳喂养医学领域的临床和研究重点。迄今为止,有四例病例报告详细说明了希望母乳喂养的变性患者成功诱导泌乳。由于缺乏高质量的研究，母乳喂养医学研究院并未正式推荐变性患者的特定药物治疗方案。病例介绍：一名50岁的变性女性，患有高凝性疾病，她能够在性别护理诊所通过新型激素方案管理进行乳酸和母乳喂养。她的基线激素治疗是雌二醇0.3mg透皮贴剂每72小时和微粉化孕酮200mg每天。结果：在开始修改的激素方案的四周内（雌二醇0.4mg贴剂每72小时，孕酮每天300毫克，甲氧氯普胺10毫克，每日三次)，患者自发泌乳。在多个场合,她母乳喂养，并通过抽水挤出30毫升的牛奶。结论：本报告为希望乳酸且无法获得多潘立酮的跨性别患者提供了一种新的有效激素方案-以前病例报告中使用的半乳糖。它还提供了以前发表的关于这一主题的病例报告的审查。该领域的未来研究应优先考虑希望哺乳的变性患者的队列研究，以进一步评估患者的态度。经验,和结果。
