关键词: Schlemm’s canal anterior scleral thickness anterior segment optical coherence tomography conjunctival thickness glaucoma high myopia trabecular meshwork

来  源:   DOI:10.3390/diagnostics14060655   PDF(Pubmed)

Abstract:
Background: To assess the anterior scleral thickness (AST), Schlemm\'s canal diameter (SCD), trabecular meshwork diameter (TMD) and conjunctiva tenon capsule thickness (CTT) in high myopic (HM) subjects and HM subjects with glaucoma (HMG) compared to control eyes. Methods: One hundred and twenty eyes were included, and AST at 0, 1, 2 and 3 mm from the scleral spur, SCD, TMD and CTT were measured. Results: Mean age was 64.2 ± 11.0 years, and the temporal SCD and temporal TMD were significantly longer in the HMG subjects compared to the controls (380.0 ± 62 μm vs. 316.7 ± 72 μm, p = 0.001) and (637.6 ± 113 μm vs. 512.1 ± 97 μm, p = 0.000), respectively. There were no significant differences between the HM and HMG subjects in SCD and TMD (all p > 0.025). Compared to the HM subjects, the temporal AST0 (432.5 ± 79 μm vs. 532.8 ± 99 μm, p = 0.000), temporal AST1 (383.9 ± 64 μm vs. 460.5 ± 80 μm, p = 0.000), temporal AST2 (404.0 ± 68 μm vs. 464.0 ± 88 μm, p = 0.006) and temporal AST3 (403.0 ± 80 μm vs. 458.1 ± 91 μm, p = 0.014) were significantly thinner in the HMG group. No differences were found between the CTT in the three groups (all p > 0.025). Conclusions: Our data indicate a thinner AST in HMG subjects and no differences in SCD and TMD between HM and HMG subjects.
摘要:
背景:评估前巩膜厚度(AST),Schlemm根管直径(SCD),与对照眼相比,高度近视(HM)受试者和患有青光眼(HMG)的HM受试者的小梁网直径(TMD)和结膜筋膜厚度(CTT)。方法:纳入120只眼,和AST在距巩膜骨刺0、1、2和3mm处,SCD,测量TMD和CTT。结果:平均年龄为64.2±11.0岁,与对照组相比,HMG受试者的时间SCD和时间TMD明显更长(380.0±62μmvs.316.7±72μm,p=0.001)和(637.6±113μmvs.512.1±97μm,p=0.000),分别。HM和HMG受试者在SCD和TMD方面没有显著差异(均p>0.025)。与HM科目相比,时间AST0(432.5±79μmvs.532.8±99μm,p=0.000),时间AST1(383.9±64μmvs.460.5±80μm,p=0.000),时间AST2(404.0±68μmvs.464.0±88μm,p=0.006)和时间AST3(403.0±80μmvs.458.1±91μm,p=0.014)在HMG组中明显变薄。三组的CTT无差异(p>0.025)。结论:我们的数据表明HMG受试者的AST较薄,而HM和HMG受试者之间的SCD和TMD没有差异。
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