PDF(Pubmed)
Abstract：
This is a retrospective study investigating biometric measurements using magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is one of the more common causes of pulmonary hypoplasia, with grave consequences for the fetus. Inclusion criteria were patients diagnosed with CDH as the only observed anomaly, who underwent MRI examination after the second-trimester morphology ultrasound. The patients came from three university hospitals in Bucharest, Romania. In total, 19 patients were included in the study after applying exclusion criteria. Comparing the observed values of the thoracic transverse diameter, the thoracic anterior-posterior diameter, the thoracic circumference, the thoracic area, and the thoracic volume with values from the literature, we observed a predictive alteration of these parameters, with most showing Gaussian distribution. We observed statistical significance for most of our correlations, except between the observed and expected thoracic anterior-posterior diameters and the observed and expected thoracic volume values. This is very helpful when complex studies that can calculate the pulmonary volume cannot be obtained, as in the case of movement artifacts, and allows the clinicians to better assess the severity of the disease. MRI follow-up in CDH cases is a necessity, as it offers the most accurate thoracic biometry.
摘要：
这是一项回顾性研究，调查了先天性膈疝（CDH）使用磁共振成像（MRI）检查进行的生物特征测量。CDH是肺发育不全的常见原因之一，会对胎儿造成严重后果.纳入标准是诊断为CDH的患者作为唯一观察到的异常，在妊娠中期形态超声检查后接受MRI检查。病人来自布加勒斯特的三家大学医院，罗马尼亚。总的来说,在应用排除标准后，19名患者被纳入研究。比较胸部横径的观察值，胸部前后直径，胸围，胸部区域,和文献中的胸腔容积，我们观察到这些参数的预测性改变，大多数显示高斯分布。我们观察到大多数相关性的统计学意义，除了观察到的和预期的胸部前后径以及观察到的和预期的胸部容积值之间。当无法获得可以计算肺体积的复杂研究时，这非常有帮助，就像运动伪影一样，并允许临床医生更好地评估疾病的严重程度。CDH病例的MRI随访是必要的，因为它提供了最准确的胸部生物特征。
