PDF(Pubmed)
Abstract：
We report the case of a woman nearing 70 years old who was admitted to the hospital with a complaint of \"epigastric distension for 1 month\". Her main signs and symptoms were progressive abdominal distension and occasional abdominal pain. Computed tomography suggested an abdominal mass. She had a surgical history of synovial sarcoma (SS) of the lungs. After admission, she was diagnosed with jejunal SS following a puncture biopsy and laparoscopic surgery. This disease usually occurs in the soft tissues of the limbs, and it is extremely rare for SS to originate in the jejunum. The morphologic heterogeneity of SS overlaps with other tumors and makes the diagnosis particularly difficult. Imaging studies usually lack specificity; however, measuring multiple immunohistochemical markers can greatly assist in the diagnosis and differential diagnosis of SS. This case not only enriches our understanding of SS and describes a rare site of origin, but also emphasizes the importance and challenges of achieving an accurate diagnosis. Immunohistochemical and molecular biological testing have important roles in the definitive diagnosis, highlighting the need for precise and innovative diagnostic and therapeutic approaches in SS.
摘要：
我们报告了一名接近70岁的妇女因“上腹部扩张1个月”而入院的病例。她的主要症状和体征是进行性腹胀和偶发腹痛。计算机断层扫描提示腹部肿块。她有肺滑膜肉瘤（SS）的手术史。入院后,在穿刺活检和腹腔镜手术后,她被诊断为空肠SS.这种疾病通常发生在四肢的软组织，SS起源于空肠极为罕见。SS的形态学异质性与其他肿瘤重叠，使诊断特别困难。影像学检查通常缺乏特异性；然而，检测多种免疫组织化学标记物可以大大有助于SS的诊断和鉴别诊断。这个案例不仅丰富了我们对SS的理解，而且描述了一个罕见的起源地点，但也强调了实现准确诊断的重要性和挑战。免疫组织化学和分子生物学检测在明确诊断中具有重要作用,强调在SS中需要精确和创新的诊断和治疗方法。
