Abstract：
Laryngeal paraganglioma (LP) is an exceptionally rare neuroendocrine tumor, underscoring importance of accurate identification to preclude misdiagnoses. In this review, we presented two typical misdiagnosed LPs, and offered reviews of LP cases reported over the preceding decade and all documented misdiagnosed LP cases. Furthermore, we systematically investigated the underlying causes of misdiagnosis and elucidated key points for effective differentiation. A retrospective analysis of 28 LP cases revealed a predominant occurrence in middle-aged women, with an average history of 25.1 months. Through an analysis of all misdiagnosed cases (n = 37), supraglottic LPs were frequently misidentified as laryngeal carcinomas and vascular tumors, while subglottic LPs were often misdiagnosed as thyroid cancers. And the occurrence of misdiagnosis resulted in delayed and inappropriate treatments, contributing to the deterioration of LP patients (14 cases, 37.8%). In conclusion, this review endeavored to heighten awareness of LPs, with the ultimate goal of advancing diagnostic precision and enhancing patient outcomes.
摘要：
喉副神经节瘤（LP）是一种非常罕见的神经内分泌肿瘤，强调准确识别以防止误诊的重要性。在这次审查中,我们提出了两个典型的误诊LP，并提供了对过去十年报告的LP病例和所有记录的误诊LP病例的审查。此外，我们系统地调查了误诊的根本原因，并阐明了有效鉴别的要点。对28例LP病例的回顾性分析显示，中年妇女主要发生，平均病史25.1个月。通过对所有误诊病例(n=37)的分析，声门上LPs经常被误认为是喉癌和血管肿瘤，而声门下LP常被误诊为甲状腺癌。误诊的发生导致延误和不适当的治疗，导致LP患者恶化(14例，37.8%）。总之,这次审查努力提高对LP的认识，最终目标是提高诊断精度和提高患者预后。
