Abstract：
We report a 30-case series from the Pain Management Center at the Massachusetts General Hospital where we have applied a guideline to convert chronic treatment for pain from full agonist opioids (FAO) to buprenorphine (BUP). Of the patients, 24 (80 percent) elected to continue BUP over FAO. Five conversions were stopped for side effects (fatigue) and/or lack of sufficient pain reduction. One patient elected not to participate on the day that the conversion was to begin. There were no major adverse events. We conclude that conversion to BUP should be considered as an alternative to treat patients on chronic opioids for pain.
摘要：
我们报告了马萨诸塞州总医院疼痛管理中心的30例病例系列，我们应用了一项指南，将慢性疼痛治疗从完全激动剂阿片类药物（FAO）转换为丁丙诺啡（BUP）。在患者中，24人（80％）当选继续参加粮农组织的联大。由于副作用（疲劳）和/或缺乏足够的疼痛减轻，停止了五次转换。一名患者选择在转换开始当天不参加。无重大不良事件发生。我们得出的结论是，转换为BUP应被视为治疗慢性阿片类药物患者疼痛的替代方法。
