PDF(Pubmed)
Abstract：
UNASSIGNED: : This systematic review aimed to provide a comparative analysis of the treatment outcomes, including hard and soft tissues, postoperative stability, temporomandibular disorders (TMD), and quality of life (QoL), in patients with facial asymmetry who underwent orthognathic surgery.
UNASSIGNED: : The primary objective was to address the question, \"How do different factors related to surgery affect the outcomes and stability of orthognathic surgery in the correction of facial asymmetry?\" A meta-analysis was conducted on the outcome parameters, such as skeletal, dental, and soft tissue symmetry, TMD, QoL, and relapse, using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Subgroup analyses were conducted considering surgery-related factors such as surgical techniques (one-jaw vs. two-jaw), use of the surgery-first approach, utilization of computer simulation, and analytical methods employed to evaluate asymmetry (2D vs. 3D).
UNASSIGNED: : Forty-nine articles met the inclusion criteria. The meta-analysis demonstrated a significant improvement in the symmetry of hard and soft tissues. The subgroup analysis indicated that the treatment outcomes showed significant improvement, regardless of the factors related to surgery. Changes in TMD signs and symptoms varied according to the surgical technique used. Quality of life improved in the facial, oral, and social domains. Skeletal relapse was observed during the follow-up.
UNASSIGNED: : Our findings support the positive outcomes of orthognathic surgery in the treatment of facial asymmetry in terms of skeletal and soft tissue improvements, stability, relief of TMD symptoms, and enhancement of QoL. However, most of the included studies showed a low certainty of evidence and high heterogeneity.
UNASSIGNED: : The primary objective was to address the question, \"How do different factors related to surgery affect the outcomes and stability of orthognathic surgery in the correction of facial asymmetry?\" A meta-analysis was conducted on the outcome parameters, such as skeletal, dental, and soft tissue symmetry, TMD, QoL, and relapse, using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Subgroup analyses were conducted considering surgery-related factors such as surgical techniques (one-jaw vs. two-jaw), use of the surgery-first approach, utilization of computer simulation, and analytical methods employed to evaluate asymmetry (2D vs. 3D).
UNASSIGNED: : Forty-nine articles met the inclusion criteria. The meta-analysis demonstrated a significant improvement in the symmetry of hard and soft tissues. The subgroup analysis indicated that the treatment outcomes showed significant improvement, regardless of the factors related to surgery. Changes in TMD signs and symptoms varied according to the surgical technique used. Quality of life improved in the facial, oral, and social domains. Skeletal relapse was observed during the follow-up.
UNASSIGNED: : Our findings support the positive outcomes of orthognathic surgery in the treatment of facial asymmetry in terms of skeletal and soft tissue improvements, stability, relief of TMD symptoms, and enhancement of QoL. However, most of the included studies showed a low certainty of evidence and high heterogeneity.
摘要：
■：本系统综述旨在对治疗结果进行比较分析，包括硬组织和软组织，术后稳定性,颞下颌关节紊乱病(TMD),和生活质量(QoL)，在接受正颌手术的面部不对称患者中。
■：主要目标是解决这个问题，“与手术相关的不同因素如何影响矫正面部不对称的正颌手术的结果和稳定性？”对结果参数进行了荟萃分析，比如骨骼，牙科,和软组织对称性，TMD,QoL,和复发，使用Hartung-Knapp-Sidik-Jonkman方法进行随机效应模型。亚组分析考虑了手术相关因素，如手术技术(单颌vs.双爪)，使用手术优先的方法，利用计算机模拟，以及用于评估不对称性的分析方法(2D与3D)。
■：49篇文章符合纳入标准。荟萃分析表明，硬组织和软组织的对称性显着改善。亚组分析表明，治疗结果显着改善，无论与手术相关的因素如何。TMD体征和症状的变化根据所使用的手术技术而有所不同。面部生活质量得到改善，口服,和社会领域。随访期间观察到骨骼复发。
■：我们的研究结果支持正颌手术在骨骼和软组织改善方面治疗面部不对称的积极结果，稳定性,缓解TMD症状，和QoL的增强。然而,大多数纳入的研究显示证据确定性低,异质性高.
■：主要目标是解决这个问题，“与手术相关的不同因素如何影响矫正面部不对称的正颌手术的结果和稳定性？”对结果参数进行了荟萃分析，比如骨骼，牙科,和软组织对称性，TMD,QoL,和复发，使用Hartung-Knapp-Sidik-Jonkman方法进行随机效应模型。亚组分析考虑了手术相关因素，如手术技术(单颌vs.双爪)，使用手术优先的方法，利用计算机模拟，以及用于评估不对称性的分析方法(2D与3D)。
■：49篇文章符合纳入标准。荟萃分析表明，硬组织和软组织的对称性显着改善。亚组分析表明，治疗结果显着改善，无论与手术相关的因素如何。TMD体征和症状的变化根据所使用的手术技术而有所不同。面部生活质量得到改善，口服,和社会领域。随访期间观察到骨骼复发。
■：我们的研究结果支持正颌手术在骨骼和软组织改善方面治疗面部不对称的积极结果，稳定性,缓解TMD症状，和QoL的增强。然而,大多数纳入的研究显示证据确定性低,异质性高.
