PDF(Pubmed)
Abstract：
UNASSIGNED: Aim of this study was to assess the impact of contrast media dose (CMD) reduction on diagnostic quality of photon-counting detector CT (PCD-CT) and energy-integrating detector CT (EID-CT).
UNASSIGNED: CT scans of the abdominal region with differing CMD acquired in portal venous phase on a PCD-CT were included and compared to EID-CT scans. Diagnostic quality and contrast intensity were rated. Additionally, readers had to assign the scans to reduced or regular CMD. Regions-of-interest (ROIs) were placed in defined segments of portal vein, inferior vena cava, liver, spleen, kidneys, abdominal aorta and muscular tissue. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated.
UNASSIGNED: Overall 158 CT scans performed on a PCD-CT and 68 examinations on an EID-CT were analyzed. Overall diagnostic quality showed no significant differences for PCD-CT with standard CMD which scored a median 5 (IQR:5-5) and PCD-CT with 70% CMD scoring 5 (4-5). (For PCD-CT, 71.69% of the examinations with reduced CMD were assigned to regular CMD by the readers, for EID-CT 9.09%. Averaged for all measurements SNR for 50% CMD was reduced by 19% in PCD-CT (EID-CT 34%) and CNR by 48% (EID-CT 56%). Virtual monoenergetic images (VMI)50keV for PCD-CT images acquired with 50% CMD showed an increase in SNR by 72% and CNR by 153%.
UNASSIGNED: Diagnostic interpretability of PCD-CT examinations with reduction of up to 50% CMD is maintained. PCD-CT deducted scans especially with 70% CMD were often not recognized as CMD reduced scans. Compared to EID-CT less decline in SNR and CNR is observed for CMD reduced PCD-CT images. Employing VMI50keV for CMD-reduced PCD-CT images compensated for the effects.
UNASSIGNED: CT scans of the abdominal region with differing CMD acquired in portal venous phase on a PCD-CT were included and compared to EID-CT scans. Diagnostic quality and contrast intensity were rated. Additionally, readers had to assign the scans to reduced or regular CMD. Regions-of-interest (ROIs) were placed in defined segments of portal vein, inferior vena cava, liver, spleen, kidneys, abdominal aorta and muscular tissue. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated.
UNASSIGNED: Overall 158 CT scans performed on a PCD-CT and 68 examinations on an EID-CT were analyzed. Overall diagnostic quality showed no significant differences for PCD-CT with standard CMD which scored a median 5 (IQR:5-5) and PCD-CT with 70% CMD scoring 5 (4-5). (For PCD-CT, 71.69% of the examinations with reduced CMD were assigned to regular CMD by the readers, for EID-CT 9.09%. Averaged for all measurements SNR for 50% CMD was reduced by 19% in PCD-CT (EID-CT 34%) and CNR by 48% (EID-CT 56%). Virtual monoenergetic images (VMI)50keV for PCD-CT images acquired with 50% CMD showed an increase in SNR by 72% and CNR by 153%.
UNASSIGNED: Diagnostic interpretability of PCD-CT examinations with reduction of up to 50% CMD is maintained. PCD-CT deducted scans especially with 70% CMD were often not recognized as CMD reduced scans. Compared to EID-CT less decline in SNR and CNR is observed for CMD reduced PCD-CT images. Employing VMI50keV for CMD-reduced PCD-CT images compensated for the effects.
摘要：
■这项研究的目的是评估造影剂剂量（CMD）减少对光子计数探测器CT（PCD-CT）和能量积分探测器CT（EID-CT）的诊断质量的影响。
■包括在PCD-CT上在门静脉期获得的具有不同CMD的腹部区域的CT扫描，并与EID-CT扫描进行比较。对诊断质量和对比强度进行评级。此外,读者必须将扫描分配给减少或常规的CMD。感兴趣的区域（ROI）被放置在确定的门静脉段，下腔静脉,肝脏,脾,脾肾脏，腹主动脉和肌肉组织。计算信噪比(SNR)和对比噪声比(CNR)。
分析了在PCD-CT上进行的158次CT扫描和在EID-CT上进行的68次检查。对于具有中位数为5的标准CMD（IQR：5-5）的PCD-CT和具有70％CMD评分为5（4-5）的PCD-CT，总体诊断质量没有显着差异。(对于PCD-CT,71.69%的CMD降低的考试由读者分配给常规CMD，对于EID-CT9.09%。对于所有测量的平均值,50%CMD的SNR在PCD-CT中降低19%(EID-CT34%),CNR降低48%(EID-CT56%)。使用50％CMD获取的PCD-CT图像的虚拟单能量图像（VMI）50keV显示SNR增加72％，CNR增加153%。
■保持PCD-CT检查的诊断可解释性,其中CMD降低高达50%。PCD-CT扣除扫描，尤其是具有70％CMD的扫描通常不被认为是CMD减少的扫描。与EID-CT相比,对于CMD减少的PCD-CT图像观察到SNR和CNR的较少下降。使用VMI50keV对CMD减少的PCD-CT图像进行补偿。
■包括在PCD-CT上在门静脉期获得的具有不同CMD的腹部区域的CT扫描，并与EID-CT扫描进行比较。对诊断质量和对比强度进行评级。此外,读者必须将扫描分配给减少或常规的CMD。感兴趣的区域（ROI）被放置在确定的门静脉段，下腔静脉,肝脏,脾,脾肾脏，腹主动脉和肌肉组织。计算信噪比(SNR)和对比噪声比(CNR)。
分析了在PCD-CT上进行的158次CT扫描和在EID-CT上进行的68次检查。对于具有中位数为5的标准CMD（IQR：5-5）的PCD-CT和具有70％CMD评分为5（4-5）的PCD-CT，总体诊断质量没有显着差异。(对于PCD-CT,71.69%的CMD降低的考试由读者分配给常规CMD，对于EID-CT9.09%。对于所有测量的平均值,50%CMD的SNR在PCD-CT中降低19%(EID-CT34%),CNR降低48%(EID-CT56%)。使用50％CMD获取的PCD-CT图像的虚拟单能量图像（VMI）50keV显示SNR增加72％，CNR增加153%。
■保持PCD-CT检查的诊断可解释性,其中CMD降低高达50%。PCD-CT扣除扫描，尤其是具有70％CMD的扫描通常不被认为是CMD减少的扫描。与EID-CT相比,对于CMD减少的PCD-CT图像观察到SNR和CNR的较少下降。使用VMI50keV对CMD减少的PCD-CT图像进行补偿。
