关键词: infectious diseases and tropical medicine respiratory disorders rheumatology

来  源:   DOI:10.1093/omcr/omae007   PDF(Pubmed)

Abstract:
Laryngeal tuberculosis (LT), a rare but possible manifestation of extrapulmonary tuberculosis (TBC) and the most frequent granulomatous disease of the larynx, is slowly resurfacing due to the worldwide recrudescence of TBC. We present the case of a 59 y-o Caucasian woman, non-smoker, with no history of recent travels in endemic areas, affected by pulmonary sarcoidosis, that presented with a symptomatic vegetating lesion involving the left free margin of the epiglottic and a small, ulcerated lesion over the right arytenoid mucosa. While the patient\'s profile would not lead to a primary suspect of laryngeal TBC, the diagnostic workup and histological examination confirmed the unusual finding, and the patient was started on standard antitubercular therapy, with a complete laryngeal response. Although isolated laryngeal tuberculosis is still a rare finding, it should be kept into consideration also in non-endemic areas, especially in patients with chronic disease requiring immunosuppressive drugs.
摘要:
喉结结核(LT),肺外结核(TBC)的罕见但可能的表现和最常见的喉部肉芽肿疾病,由于TBC在全球范围内的复发,正在缓慢地重新出现。我们介绍了一个59岁的白人女性的案例,非吸烟者,没有最近在流行地区旅行的历史,受肺结节病影响,表现为症状性植被病变,涉及会厌的左自由缘和小,右侧Arytenoid粘膜上的溃疡病变。虽然患者的资料不会导致喉部TBC的主要嫌疑人,诊断检查和组织学检查证实了这一异常发现,病人开始接受标准的抗结核治疗,喉部有完全的反应.虽然孤立的喉结结核仍然是一个罕见的发现,在非流行地区也应考虑到这一点,尤其是需要免疫抑制药物的慢性病患者。
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