PDF(Pubmed)
Abstract：
Penile calciphylaxis is a rare presentation of calcific uremic arteriolopathy and can be a life-threatening condition usually seen in patients with end-stage renal failure with hemodialysis. The clear etiopathogenesis of calciphylaxis is not fully understood, but it is postulated to be characterized by the accumulation of calcium in the microvessels of adipose tissue and skin, which leads to ischemia and necrosis, causing painful ulcerations, and could potentially be complicated by sepsis and mortality. End-stage renal disease (ESRD) is one of the major risk factors for penile calciphylaxis. In this report, we describe a case of a 53-year-old Hispanic male patient with ESRD and diabetes on hemodialysis, who presented with a five-day history of acute, severe, burning, non-radiating pain to the head of his penis associated with black discoloration. He was diagnosed with penile calciphylaxis and received a combination of conservative and surgical interventions, resulting in a highly positive outcome marked by complete healing of the scar without any reported complications.
摘要：
阴茎钙化是钙化性尿毒症小动脉病变的罕见表现，可能是一种威胁生命的疾病，通常见于血液透析的终末期肾衰竭患者。钙化的明确病因尚未完全了解，但据推测，它的特征是钙在脂肪组织和皮肤的微血管中积累，导致缺血和坏死，导致疼痛的溃疡,并可能因败血症和死亡率而复杂化。终末期肾病（ESRD）是阴茎钙化的主要危险因素之一。在这份报告中,我们描述了一例53岁的西班牙裔男性ESRD和糖尿病患者的血液透析，他有五天的急性病史，严重,燃烧,与黑色变色有关的阴茎头部非放射状疼痛。他被诊断出患有阴茎钙化症，并接受了保守和手术相结合的干预措施，产生高度阳性的结果，其特征是瘢痕完全愈合，没有任何报告的并发症。
