UNASSIGNED: The laxative activity of A. abyssinica leaf and stem extracts was evaluated using three models: laxative activity, gastrointestinal motility, and gastrointestinal secretion. In this study, bisacodyl was used as a standard laxative and loperamide was used to induce constipation.
UNASSIGNED: In the laxative test, 200 (P<0.05) and 400 mg/kg (p<0.01) doses of plant extract significantly increased the percentage of fecal water content. Moreover, the highest dose of extract increased the frequency of defecation after 12 h (p<0.05). In the remaining two models, the experimental plans also showed significantly higher gastrointestinal motility and noticeable accumulation of intestinal fluid.
UNASSIGNED: The results of this study indicate that aqueous leaf and stem extracts of A. abyssinica have laxative effects.
■使用三种模型评估了深参叶和茎提取物的泻药活性:泻药活性,胃肠蠕动,和胃肠分泌。在这项研究中,比沙可啶被用作标准泻药,洛哌丁胺被用于诱发便秘。
■在泻药试验中,200(P<0.05)和400mg/kg(p<0.01)剂量的植物提取物显着增加了粪便含水量的百分比。此外,最高剂量的提取物增加了12h后排便的频率(p<0.05)。在剩下的两个模型中,实验计划还显示出明显更高的胃肠蠕动和明显的肠液积累。
■这项研究的结果表明,A.abysinica的水性叶和茎提取物具有通便作用。