PDF(Pubmed)
Abstract：
\"Long COVID\" is a term used to describe a condition when the symptoms and signs associated with coronavirus disease 2019 (COVID-19) persist for more than three months among patients infected with COVID-19; this condition has been reported globally and poses a serious public health issue. Long COVID can manifest in various forms, highlighting the need for appropriate evaluation and management by experts from various fields. However, due to the lack of clear clinical definitions, knowledge of pathophysiology, diagnostic methods, and treatment protocols, it is necessary to develop the best standard clinical guidelines based on the scientific evidence reported to date. We developed this clinical guideline for diagnosing and treating long COVID by analyzing the latest research data collected from the start of the COVID-19 pandemic until June 2023, along with the consensus of expert opinions. This guideline provides recommendations for diagnosis and treatment that can be applied in clinical practice, based on a total of 32 key questions related to patients with long COVID. The evaluation of patients with long COVID should be comprehensive, including medical history, physical examination, blood tests, imaging studies, and functional tests. To reduce the risk of developing long COVID, vaccination and antiviral treatment during the acute phase are recommended. This guideline will be revised when there is a reasonable need for updates based on the availability of new knowledge on the diagnosis and treatment of long COVID.
摘要：
“长COVID”是一个术语，用于描述与2019年冠状病毒病(COVID-19)相关的症状和体征在感染COVID-19的患者中持续超过三个月；这种情况已在全球范围内报道，并构成严重的公共卫生问题。长COVID可以以各种形式出现，强调需要由各个领域的专家进行适当的评估和管理。然而,由于缺乏明确的临床定义，病理生理学知识，诊断方法,和治疗方案，有必要根据迄今报道的科学证据制定最佳的标准临床指南.我们通过分析从COVID-19大流行开始到2023年6月收集的最新研究数据，以及专家意见的共识，制定了诊断和治疗长期COVID的临床指南。本指南提供了可应用于临床实践的诊断和治疗建议，基于总共32个与长型COVID患者相关的关键问题。对长期COVID患者的评估应该是全面的，包括病史,体检,验血,影像学检查,和功能测试。为了降低长发COVID的风险，建议在急性期进行疫苗接种和抗病毒治疗。当根据长期COVID诊断和治疗的新知识的可用性有合理的更新需要时，将修订本指南。
