Abstract：
As the body\'s largest organ, the skin is located at the internal and external environment interface, serving as a line of defense against various harmful stressors. Recently, marine-derived physiologically active ingredients have attracted considerable attention in the cosmeceutical industry due to their beneficial effects on skin health. Sargassum, a genus of brown macroalgae, has traditionally been consumed as food and medicine in several countries and is rich in bioactive compounds such as meroterpenoids, sulfated polysaccharides, fucoidan, fucoxanthin, flavonoids, and terpenoids. Sargassum spp. have various beneficial effects on skin disorders. They help with atopic dermatitis by improving skin barrier protection and reducing inflammation. Several species show potential in treating acne by inhibiting bacterial growth and reducing inflammation. Some species, such as Sargassum horneri, demonstrate antiallergic effects by modulating mast cell activity. Certain Sargassum species exhibit anticancer activity by inhibiting tumor growth and promoting apoptosis, and some species help with wound healing by promoting angiogenesis and reducing oxidative stress. Overall, Sargassum spp. demonstrate potential for treating and managing various skin conditions. Therefore, the bioactive compounds of Sargassum spp. may be natural ingredients with a wide range of functional properties for preventing and treating skin disorders. The present review focused on the various biological effects of Sargassum extracts and derived compounds on skin disorders.
摘要：
作为人体最大的器官,皮肤位于内外环境界面，作为抵御各种有害压力的防线。最近,海洋衍生的生理活性成分由于其对皮肤健康的有益作用而在药妆行业中引起了相当大的关注。Sargassum,棕色大型藻类的一个属，传统上在几个国家被用作食品和药品，并且富含生物活性化合物，硫酸多糖，岩藻聚糖,岩藻黄质,黄酮类化合物，和萜类化合物.马尾藻属。对皮肤病有各种有益作用。它们通过改善皮肤屏障保护和减少炎症来帮助特应性皮炎。一些物种显示出通过抑制细菌生长和减少炎症来治疗痤疮的潜力。一些物种,比如Sargassumhorneri,通过调节肥大细胞活性证明抗过敏作用。某些马尾藻物种通过抑制肿瘤生长和促进细胞凋亡而表现出抗癌活性，一些物种通过促进血管生成和减少氧化应激来帮助伤口愈合。总的来说,马尾藻属。展示治疗和管理各种皮肤状况的潜力。因此,马尾藻属的生物活性化合物。可以是具有用于预防和治疗皮肤病的广泛功能性质的天然成分。本综述集中于马尾藻提取物和衍生化合物对皮肤病的各种生物学作用。
