PDF(Pubmed)
Abstract：
UNASSIGNED: Second to COVID-19 pandemic, other viral respiratory infections are still important causes of human diseases or co-infections. Hence, the present study was carried out to investigate the common respiratory viruses in patients with respiratory illness diagnosed negative for severe acute respiratory syndrome coronavirus-2 in primary screening.
UNASSIGNED: In a cross-sectional study, a real-time PCR was carried out using HiTeq. 17 Viro Respiratory pathogen One Step RT-PCR Kit (Genova, Bonda Faravar, Bioluence, Tehran, Iran).
UNASSIGNED: A total of 311 individuals (mean age ± SD: 48.2 ± 21.7 years, range: 1-97 years) underwent second PCR. Among these, 161 (51.7%) were female. In total, 55 (17.6%) cases (mean age ± SD: 45.7 ± 18.1 years) were found positive for respiratory viruses panel in the second PCR. The HCoV-OC43/HKU1 was in 5.4% (17/311), Flu A in 4.5% (14/311), HCoV-229E/NL63 in 2.8% (9/311), HMPV in 1.9% (6/311), HPiV 1, 2, 3 in 1.2% (4/311), HRSV in 0.9% (3/311), and HAdV in 0.6% (2/311) of the cases studies. Also, co-infection was detected in 4 samples (1.2%). In addition, sore throat (0.028), headache (p = 0.016), and body pain (p = 0.0001) were statistically the most significant symptoms in studied cases.
UNASSIGNED: According to the findings of our study, respiratory virus infections and co-infections were 17.6% and 1.2% frequent, respectively. Interestingly, nearly half of our positive cases (47.2%) were identified by coronaviruses (ОС43, Е229, NL63, and HKUI), followed by influenza A virus (25.4%). However, for more comprehensive results, we recommend using greater sample size.
UNASSIGNED: In a cross-sectional study, a real-time PCR was carried out using HiTeq. 17 Viro Respiratory pathogen One Step RT-PCR Kit (Genova, Bonda Faravar, Bioluence, Tehran, Iran).
UNASSIGNED: A total of 311 individuals (mean age ± SD: 48.2 ± 21.7 years, range: 1-97 years) underwent second PCR. Among these, 161 (51.7%) were female. In total, 55 (17.6%) cases (mean age ± SD: 45.7 ± 18.1 years) were found positive for respiratory viruses panel in the second PCR. The HCoV-OC43/HKU1 was in 5.4% (17/311), Flu A in 4.5% (14/311), HCoV-229E/NL63 in 2.8% (9/311), HMPV in 1.9% (6/311), HPiV 1, 2, 3 in 1.2% (4/311), HRSV in 0.9% (3/311), and HAdV in 0.6% (2/311) of the cases studies. Also, co-infection was detected in 4 samples (1.2%). In addition, sore throat (0.028), headache (p = 0.016), and body pain (p = 0.0001) were statistically the most significant symptoms in studied cases.
UNASSIGNED: According to the findings of our study, respiratory virus infections and co-infections were 17.6% and 1.2% frequent, respectively. Interestingly, nearly half of our positive cases (47.2%) were identified by coronaviruses (ОС43, Е229, NL63, and HKUI), followed by influenza A virus (25.4%). However, for more comprehensive results, we recommend using greater sample size.
摘要：
■仅次于COVID-19大流行，其他呼吸道病毒感染仍然是人类疾病或合并感染的重要原因。因此，本研究旨在调查初筛中严重急性呼吸综合征冠状病毒-2阴性的呼吸系统疾病患者的常见呼吸道病毒。
■在一项横断面研究中，使用HiTeq进行实时PCR。17病毒呼吸道病原体一步RT-PCR试剂盒(Genova，邦达·法拉瓦,Bioluence,德黑兰,伊朗)。
■共有311人（平均年龄±SD：48.2±21.7岁，范围：1-97年）进行了第二次PCR。其中,161名（51.7%）为女性。总的来说,在第二次PCR中发现55（17.6％）例（平均年龄±SD：45.7±18.1岁）呼吸道病毒阳性。HCoV-OC43/HKU1为5.4％（17/311），甲型流感占4.5%(14/311)，HCoV-229E/NL63为2.8%（9/311），HMPV为1.9%（6/311），HPiV1、2、3的1.2%(4/311)，HRSV为0.9%（3/311），和HAdV在0.6%(2/311)的病例研究中。此外，在4份样本中检测到共感染(1.2%)。此外,喉咙痛（0.028），头痛（p=0.016），和身体疼痛（p=0.0001）在统计学上是研究病例中最显著的症状。
■根据我们的研究结果，呼吸道病毒感染和合并感染的频率分别为17.6%和1.2%，分别。有趣的是,我们近一半的阳性病例(47.2%)是由冠状病毒鉴定的(43、229、NL63和HKUI)，其次是甲型流感病毒(25.4%)。然而,为了获得更全面的结果，我们建议使用更大的样本量。
■在一项横断面研究中，使用HiTeq进行实时PCR。17病毒呼吸道病原体一步RT-PCR试剂盒(Genova，邦达·法拉瓦,Bioluence,德黑兰,伊朗)。
■共有311人（平均年龄±SD：48.2±21.7岁，范围：1-97年）进行了第二次PCR。其中,161名（51.7%）为女性。总的来说,在第二次PCR中发现55（17.6％）例（平均年龄±SD：45.7±18.1岁）呼吸道病毒阳性。HCoV-OC43/HKU1为5.4％（17/311），甲型流感占4.5%(14/311)，HCoV-229E/NL63为2.8%（9/311），HMPV为1.9%（6/311），HPiV1、2、3的1.2%(4/311)，HRSV为0.9%（3/311），和HAdV在0.6%(2/311)的病例研究中。此外，在4份样本中检测到共感染(1.2%)。此外,喉咙痛（0.028），头痛（p=0.016），和身体疼痛（p=0.0001）在统计学上是研究病例中最显著的症状。
■根据我们的研究结果，呼吸道病毒感染和合并感染的频率分别为17.6%和1.2%，分别。有趣的是,我们近一半的阳性病例(47.2%)是由冠状病毒鉴定的(43、229、NL63和HKUI)，其次是甲型流感病毒(25.4%)。然而,为了获得更全面的结果，我们建议使用更大的样本量。
