关键词: Campylobacter bacteremia enteritis outcome

来  源:   DOI:10.1093/ofid/ofae131   PDF(Pubmed)

Abstract:
UNASSIGNED: Bacteremia with species in the genus Campylobacter is rare, and knowledge of the disease course in comparison with Campylobacter enteritis is limited.
UNASSIGNED: This is a retrospective population-based study. Episodes of Campylobacter bacteremia and Campylobacter enteritis with a concurrent negative blood culture result that occurred between 2015 and 2022 in southern Sweden were identified through the laboratory database. Medical records were reviewed, and clinical features between patients with bacteremic Campylobacter infections were compared with patients with Campylobacter spp found in feces.
UNASSIGNED: The study included 29 bacteremic infections with Campylobacter and 119 cases of Campylobacter spp found in feces. Patients with Campylobacter bacteremia were significantly older than those with enteritis (72 years [IQR, 58-62] vs 58 years [IQR, 33-67], P < .0001). Eleven patients with bacteremia developed sepsis within 48 hours from blood culturing, and no patient died within 30 days from hospital admission.
UNASSIGNED: Campylobacter bacteremia is rare and occurs mainly in the elderly with comorbidities. In comparison with Campylobacter infections limited to the gastrointestinal tract, patients with bacteremic Campylobacter infections are older and seem more prone to develop sepsis. Classical gastroenteritis symptoms in bacteremic cases with Campylobacter may be absent.
摘要:
弯曲杆菌属的菌血症很少见,与弯曲杆菌肠炎相比,对病程的了解有限。
这是一项基于人群的回顾性研究。通过实验室数据库确定了瑞典南部在2015年至2022年之间发生的弯曲杆菌菌血症和弯曲杆菌肠炎的发作,同时血液培养结果为阴性。检查了医疗记录,比较了菌血症性弯曲杆菌感染患者与粪便中发现弯曲杆菌的患者之间的临床特征。
该研究包括29例弯曲杆菌的细菌感染和119例粪便中发现的弯曲杆菌。弯曲杆菌菌血症患者的年龄明显高于肠炎患者(72岁[IQR,58-62]vs58岁[IQR,33-67],P<.0001)。11例菌血症患者在血液培养后48小时内出现败血症,并且没有患者在入院后30天内死亡。
弯曲杆菌菌血症很少见,主要发生在有合并症的老年人中。与局限于胃肠道的弯曲杆菌感染相比,菌血症性弯曲杆菌感染患者年龄较大,似乎更容易发生败血症.在弯曲杆菌的菌血症病例中,可能没有经典的胃肠炎症状。
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