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Abstract：
Mycobacterium gordonae (MG) is one of the least pathogenic nontuberculous mycobacteria (NTM). We report an unusual case of MG infection in a patient with newly diagnosed lung cancer. A 61-year-old woman presented with shortness of breath and weight loss. Six months prior to admission, she was diagnosed with MG infection based on positive sputum cultures and bronchioalveolar lavage. Despite anti-mycobacterial therapy, her symptoms worsened and she lost approximately 100 pounds. A transbronchial biopsy obtained one week prior to admission revealed adenocarcinoma of the lung. At admission, vital signs were normal, and a physical exam revealed bilateral crackles. Computed tomography (CT) scan of the chest revealed infiltrates with ground-glass opacity. The patient was admitted to the oncology service for evaluation. Our findings suggest that symptomatic individuals with positive cultures of MG should proceed with extensive workup for possible underlying lung cancer especially if not responding to anti-mycobacterial therapy.
摘要：
格氏分枝杆菌（MG）是致病性最低的非结核分枝杆菌（NTM）之一。我们报告了一名新诊断的肺癌患者中MG感染的异常病例。一名61岁的妇女出现呼吸急促和体重减轻。入院前六个月，根据痰培养和支气管肺泡灌洗阳性,她被诊断为MG感染.尽管抗分枝杆菌治疗,她的症状恶化，减掉了大约100磅。入院前一周进行的经支气管活检显示肺腺癌。入院时,生命体征正常,体格检查发现双侧有裂纹。胸部计算机断层扫描（CT）扫描显示浸润有毛玻璃混浊。患者被送入肿瘤学服务进行评估。我们的发现表明，MG培养阳性的有症状个体应进行广泛的检查，以治疗可能的潜在肺癌，尤其是如果对抗分枝杆菌疗法没有反应。
