PDF(Pubmed)
Abstract：
Pilomatrixoma or pilomatricoma is a benign adnexal neoplasm originating from the hair matrix, the inner sheath of the hair follicle, and the hair cortex. Although it is considered rare in adults, numerous cases have been documented in the literature. We present a case of an elderly male who sought consultation due to a newly appearing nodular lesion on his left forearm. Several benign and malignant entities were included in the original differential diagnosis. High-frequency ultrasonographic features suggested a cystic neoplasm with calcification and mild intralesional vascularity. Ultimately, histopathological examination confirmed the diagnosis of pilomatricoma. In this study, our aim is to review the importance of the available diagnostic tools, such as dermoscopy, and the emerging utility of cutaneous high-frequency ultrasonography. Some rarer pathological variants are also discussed, including perforating, anetodermic, bullous and pigmented pilomatricoma. We hope that exposure to these clinical, dermoscopic, ultrasonographic, and histopathological images will encourage clinicians to consider pilomatricoma in their differential diagnosis when approaching nodular lesions, regardless of location and patient\'s age.
摘要：
毛管瘤或毛管瘤是一种起源于毛发基质的良性附件肿瘤，毛囊的内鞘，和头发皮层。虽然它在成年人中被认为是罕见的，文献中记录了许多案例。我们介绍了一例老年男性，由于其左前臂上新出现的结节性病变而寻求咨询。最初的鉴别诊断包括几个良性和恶性实体。高频超声特征提示囊性肿瘤伴钙化和轻度病灶内血管分布。最终,组织病理学检查证实诊断为毛囊瘤。在这项研究中,我们的目标是审查可用诊断工具的重要性，比如皮肤镜检查，以及皮肤高频超声检查的新兴应用。还讨论了一些罕见的病理变异，包括射孔,止痛药，大疱性和色素性绒毛瘤。我们希望接触这些临床，皮肤镜,超声检查,和组织病理学图像将鼓励临床医生在接近结节性病变时在鉴别诊断中考虑毛囊瘤，无论地点和病人的年龄。
