Abstract：
MORF4 (mortality factor on chromosome 4)-related gene 15 (MRG15) is a chromodomain protein that exists in various multiprotein complexes involved in transcription, DNA repair, and development. Here we summarize the recent advances involving MRG15 in modulating liver metabolism, both through its chromatin-binding capability and independently of it, highlighting MRG15 as a potential therapeutic target for liver metabolic diseases.
摘要：
MORF4（染色体4上的死亡率因子）相关基因15（MRG15）是一种色域蛋白，存在于参与转录的各种多蛋白复合物中，DNA修复,和发展。在这里，我们总结了MRG15在调节肝脏代谢方面的最新进展，无论是通过它的染色质结合能力，还是独立于它，强调MRG15是肝脏代谢性疾病的潜在治疗靶点。
