Abstract:
Hungatella species, including Hungatella hathewayi and Hungatella effluvii, previously identified as part of the Clostridium genus, are anaerobic bacteria primarily residing in the gut microbiome, with infrequent implications in human infections. This article presents the case of an 87-year-old Asian male admitted for a hyperosmolar hyperglycemic state with septic shock secondary to Hungatella hathewayi bacteremia originating from acute appendicitis. Remarkably, the bacterium was detected in the blood 48 hours before the emergence of clinical and radiographic evidence of acute appendicitis. Additionally, we conducted a literature review to identify all documented human infections caused by Hungatella species. Timely microbial identification in such cases is essential for implementing targeted antibiotic therapy and optimizing clinical outcomes.
摘要:
匈牙利物种,包括Hungatellahathewayi和Hungatellaeffluvii,先前被确定为梭菌属的一部分,厌氧细菌主要存在于肠道微生物组中,对人类感染的影响很少。本文介绍了一名87岁的亚洲男性因急性阑尾炎引起的Hungatellahathewayi菌血症继发的高渗性高血糖状态并发感染性休克的病例。值得注意的是,在出现急性阑尾炎的临床和影像学证据前48小时,在血液中检测到细菌。此外,我们进行了文献综述,以确定所有由Hungatella物种引起的人类感染.在这种情况下,及时的微生物鉴定对于实施靶向抗生素治疗和优化临床结果至关重要。