PDF(Pubmed)
Abstract：
UNASSIGNED: Facial weakness is a key feature of facioscapulohumeral muscular dystrophy (FSHD) and may lead to altered facial expression and subsequent psychosocial impairment. There is no cure and supportive treatments focus on optimizing physical fitness and compensation of functional disabilities.
UNASSIGNED: We hypothesize that symptomatic treatment options and psychosocial interventions for other neurological diseases with altered facial expression could be applicable to FSHD. Therefore, the aim of this review is to collect symptomatic treatment approaches that target facial muscle function and psychosocial interventions in various neurological diseases with altered facial expression in order to discuss the applicability to FSHD.
UNASSIGNED: A systematic search was performed. Selected studies had to include FSHD, Bell\'s palsy, Moebius syndrome, myotonic dystrophy type 1, or Parkinson\'s disease and treatment options which target altered facial expression. Data was extracted for study and patients\' characteristics, outcome assessment tools, treatment, outcome of facial expression and or psychosocial functioning.
UNASSIGNED: Forty studies met the inclusion criteria, of which only three studies included FSHD patients exclusively. Most, twenty-one, studies were performed in patients with Bell\'s palsy. Studies included twelve different therapy categories and results were assessed with different outcomes measures.
UNASSIGNED: Five therapy categories were considered applicable to FSHD: training of (non-verbal) communication compensation strategies, speech training, physical therapy, conference attendance, and smile restoration surgery. Further research is needed to establish the effect of these therapies in FSHD. We recommend to include outcome measures in these studies that cover at least cosmetic, functional, communication, and quality of life domains.
UNASSIGNED: We hypothesize that symptomatic treatment options and psychosocial interventions for other neurological diseases with altered facial expression could be applicable to FSHD. Therefore, the aim of this review is to collect symptomatic treatment approaches that target facial muscle function and psychosocial interventions in various neurological diseases with altered facial expression in order to discuss the applicability to FSHD.
UNASSIGNED: A systematic search was performed. Selected studies had to include FSHD, Bell\'s palsy, Moebius syndrome, myotonic dystrophy type 1, or Parkinson\'s disease and treatment options which target altered facial expression. Data was extracted for study and patients\' characteristics, outcome assessment tools, treatment, outcome of facial expression and or psychosocial functioning.
UNASSIGNED: Forty studies met the inclusion criteria, of which only three studies included FSHD patients exclusively. Most, twenty-one, studies were performed in patients with Bell\'s palsy. Studies included twelve different therapy categories and results were assessed with different outcomes measures.
UNASSIGNED: Five therapy categories were considered applicable to FSHD: training of (non-verbal) communication compensation strategies, speech training, physical therapy, conference attendance, and smile restoration surgery. Further research is needed to establish the effect of these therapies in FSHD. We recommend to include outcome measures in these studies that cover at least cosmetic, functional, communication, and quality of life domains.
摘要：
■面部无力是面肩肱肌营养不良症（FSHD）的一个关键特征，并可能导致面部表情改变和随后的心理社会损害。没有治愈和支持性治疗方法侧重于优化身体健康和补偿功能障碍。
■我们假设其他面部表情改变的神经系统疾病的对症治疗和心理社会干预措施可能适用于FSHD。因此,本综述的目的是收集针对面部表情改变的各种神经系统疾病的面部肌肉功能和心理社会干预的对症治疗方法,以讨论其对FSHD的适用性.
■进行了系统搜索。选定的研究必须包括FSHD，贝尔麻痹，莫比乌斯综合征,强直性肌营养不良1型，或帕金森病和治疗方案，以改变面部表情为目标。提取数据用于研究和患者特征，结果评估工具，治疗,面部表情和/或心理社会功能的结果。
■40项研究符合纳入标准，其中只有三项研究仅包括FSHD患者。大多数,21、对贝尔麻痹患者进行了研究。研究包括12种不同的治疗类别，并以不同的结果指标评估结果。
■五个治疗类别被认为适用于FSHD：（非语言）沟通补偿策略的训练，言语训练,物理治疗,会议出席,和微笑恢复手术。需要进一步的研究来确定这些疗法在FSHD中的作用。我们建议在这些研究中包括至少涵盖化妆品的结局指标，功能，通信,和生活质量领域。
■我们假设其他面部表情改变的神经系统疾病的对症治疗和心理社会干预措施可能适用于FSHD。因此,本综述的目的是收集针对面部表情改变的各种神经系统疾病的面部肌肉功能和心理社会干预的对症治疗方法,以讨论其对FSHD的适用性.
■进行了系统搜索。选定的研究必须包括FSHD，贝尔麻痹，莫比乌斯综合征,强直性肌营养不良1型，或帕金森病和治疗方案，以改变面部表情为目标。提取数据用于研究和患者特征，结果评估工具，治疗,面部表情和/或心理社会功能的结果。
■40项研究符合纳入标准，其中只有三项研究仅包括FSHD患者。大多数,21、对贝尔麻痹患者进行了研究。研究包括12种不同的治疗类别，并以不同的结果指标评估结果。
■五个治疗类别被认为适用于FSHD：（非语言）沟通补偿策略的训练，言语训练,物理治疗,会议出席,和微笑恢复手术。需要进一步的研究来确定这些疗法在FSHD中的作用。我们建议在这些研究中包括至少涵盖化妆品的结局指标，功能，通信,和生活质量领域。
