PDF(Pubmed)
Abstract：
UNASSIGNED: To identify and describe characteristics of Randomised Control Trial (RCT) design, implementation, and interpretation with a view tostrengtheningen the cultural integrity and scientific quality of this genre of research when used with, for and by Indigenous peoples.
UNASSIGNED: RCTs are widely regarded as the \'gold standard\' method for evaluating the efficacy of an intervention. However, issues of cultural acceptability and higher attrition rates among RCT participants from diverse populations, including Indigenous participants, have been reported. A better understanding of cultural acceptability and attrition rates of RCTs has the potential to impact the translation of findings into effective policies, programs and practice.
UNASSIGNED: A search of four electronic databases identified papers describing RCTs enrolling exclusively Australian Indigenous peoples over a 20-year period. The RCTs were assessed using: The Effective Public Health Practice Project\'s Quality Assessment Tool (EPHPP) and the Aboriginal & Torres Strait Islander Quality Appraisal Tool (QAT). The scores for each paper and the average scores of all papers were visualised using a Microsoft Excel™ Filled Radar Plot.
UNASSIGNED: Seventeen trials met the inclusion criteria. There was wide variation in the quality of the included trials as assessed by the EPHPP and almost universally poor results when assessed for cultural appropriateness and integrity by the QAT.
UNASSIGNED: The value of the RCT research method, when applied to ultimately improve Australian Indigenous peoples\' health, is diminished if issues of cultural integrity are not intrinsic to study design and execution. Our review found that it is feasible to have an RCT with both strong cultural integrity and high scientific quality. Attention to cultural integrity and community engagement, along with methodological rigour, may strengthen community ownership and contribute to more successful study adherence and potentially more effective translation of study findings into policy and practice.
UNASSIGNED: RCTs are widely regarded as the \'gold standard\' method for evaluating the efficacy of an intervention. However, issues of cultural acceptability and higher attrition rates among RCT participants from diverse populations, including Indigenous participants, have been reported. A better understanding of cultural acceptability and attrition rates of RCTs has the potential to impact the translation of findings into effective policies, programs and practice.
UNASSIGNED: A search of four electronic databases identified papers describing RCTs enrolling exclusively Australian Indigenous peoples over a 20-year period. The RCTs were assessed using: The Effective Public Health Practice Project\'s Quality Assessment Tool (EPHPP) and the Aboriginal & Torres Strait Islander Quality Appraisal Tool (QAT). The scores for each paper and the average scores of all papers were visualised using a Microsoft Excel™ Filled Radar Plot.
UNASSIGNED: Seventeen trials met the inclusion criteria. There was wide variation in the quality of the included trials as assessed by the EPHPP and almost universally poor results when assessed for cultural appropriateness and integrity by the QAT.
UNASSIGNED: The value of the RCT research method, when applied to ultimately improve Australian Indigenous peoples\' health, is diminished if issues of cultural integrity are not intrinsic to study design and execution. Our review found that it is feasible to have an RCT with both strong cultural integrity and high scientific quality. Attention to cultural integrity and community engagement, along with methodological rigour, may strengthen community ownership and contribute to more successful study adherence and potentially more effective translation of study findings into policy and practice.
摘要：
■为了确定和描述随机对照试验（RCT）设计的特征，实施，和解释，以期加强这种研究体裁的文化完整性和科学质量，为和土著人民。
■RCT被广泛认为是评估干预效果的“黄金标准”方法。然而,来自不同人群的RCT参与者的文化可接受性和更高的流失率问题，包括土著参与者，已被报道。更好地了解RCT的文化可接受性和流失率有可能影响将调查结果转化为有效的政策，方案和实践。
■搜索四个电子数据库，确定了描述RCT在20年期间专门招募澳大利亚土著人民的论文。使用有效公共卫生实践项目的质量评估工具（EPHPP）和原住民和托雷斯海峡岛民质量评估工具（QAT）对RCT进行评估。使用MicrosoftExcel™填充雷达图可视化每篇论文的分数和所有论文的平均分数。
■17项试验符合纳入标准。EPHPP评估的纳入试验的质量差异很大，QAT评估的文化适宜性和完整性时，结果几乎普遍较差。
■RCT研究方法的价值，当应用于最终改善澳大利亚土著人民的健康时，如果文化完整性问题不是研究设计和执行所固有的，则会减少。我们的审查发现，具有强大的文化完整性和高科学素质的RCT是可行的。注意文化完整性和社区参与，随着方法论的严谨，可以加强社区所有权，并有助于更成功地坚持研究，并可能更有效地将研究结果转化为政策和实践。
■RCT被广泛认为是评估干预效果的“黄金标准”方法。然而,来自不同人群的RCT参与者的文化可接受性和更高的流失率问题，包括土著参与者，已被报道。更好地了解RCT的文化可接受性和流失率有可能影响将调查结果转化为有效的政策，方案和实践。
■搜索四个电子数据库，确定了描述RCT在20年期间专门招募澳大利亚土著人民的论文。使用有效公共卫生实践项目的质量评估工具（EPHPP）和原住民和托雷斯海峡岛民质量评估工具（QAT）对RCT进行评估。使用MicrosoftExcel™填充雷达图可视化每篇论文的分数和所有论文的平均分数。
■17项试验符合纳入标准。EPHPP评估的纳入试验的质量差异很大，QAT评估的文化适宜性和完整性时，结果几乎普遍较差。
■RCT研究方法的价值，当应用于最终改善澳大利亚土著人民的健康时，如果文化完整性问题不是研究设计和执行所固有的，则会减少。我们的审查发现，具有强大的文化完整性和高科学素质的RCT是可行的。注意文化完整性和社区参与，随着方法论的严谨，可以加强社区所有权，并有助于更成功地坚持研究，并可能更有效地将研究结果转化为政策和实践。
