Abstract:
Radiofrequency ablation (RFA) has been a central therapeutic strategy for ventricular tachycardia (VT). However, concerns about its long-term effectiveness and complications have arisen. Pulsed field ablation (PFA), characterized by its nonthermal, highly tissue-selective ablation technique, has emerged as a promising alternative. This comprehensive review delves into the potential advantages and opportunities presented by PFA in the realm of VT, drawing insights from both animal experimentation and clinical case studies. PFA shows promise in generating superior lesions within scarred myocardial tissue, and its inherent repetition dependency holds the potential to enhance therapeutic outcomes. Clinical cases underscore the promise of PFA for VT ablation. Despite its promising applications, challenges such as catheter maneuverability and proarrhythmic effects require further investigation. Large-scale, long-term studies are essential to establish the suitability of PFA for VT treatment.
摘要:
射频消融(RFA)已成为室性心动过速(VT)的中心治疗策略。然而,对其长期有效性和并发症的担忧已经出现。脉冲场消融(PFA),其特点是无热,高度组织选择性消融技术,已经成为一个有希望的替代方案。这篇全面的综述深入探讨了PFA在VT领域的潜在优势和机遇,从动物实验和临床案例研究中汲取见解。PFA显示出在瘢痕心肌组织内产生上损伤的希望,及其固有的重复依赖性具有增强治疗效果的潜力。临床病例强调了PFA用于VT消融的前景。尽管其应用前景广阔,导管可操作性和致心律失常效应等挑战需要进一步研究.大规模,长期研究对于确定PFA用于VT治疗的适用性至关重要.