PDF(Pubmed)
Abstract：
In 2020 the World Health organization announced a pandemic due to the outbreak of the Coronavirus disease 19. Pneumonia was the most common manifestation of the Sars-Cov-2 infection, however, clinical papers describe Sars-Cov-2 associated cardiovascular pathologies, such as ACS, myopericarditis, cardiomyopathies, dysrhythmias, as leading causes of increased morbidity and mortality. The short and long term prognosis of Sars-Cov-2-related cardiovascular diseases was defined not only by the disease severity itself but also by associated conditions and complications, among which mental health issues (stress, depression and anxiety) have a negative impact. The interplay between Sars-Cov-2 infection, cardiovascular disease and depression may be explained by hyperinflammation, unhealthy lifestyle and inter-organ communication, mediated by extracellular vesicles (EV) and non-coding MicroRNA (miRNA). The long Covid syndrome is characterized with orthostatic hypotension, impaired cardiac and cerebral perfusion, postural orthostatic tachycardia syndrome (POTS), syncope, chest pain, dyspnea, palpitation, chronic fatigue syndrome, \'brain fog\', memory, cognitive and sleep difficulties, depression and anxiety. From a clinical point of view these symptoms may be considered as common symptoms representing not only a cardiac but also a neurological/psychiatric problem. Consequently assessment of these symptoms are of paramount importance. Due to their complexity, management of these patients requires multidisciplinary care.
摘要：
2020年，世界卫生组织宣布因冠状病毒病19的爆发而爆发大流行。肺炎是Sars-Cov-2感染最常见的表现，然而,临床论文描述了Sars-Cov-2相关的心血管疾病，比如ACS,心肌心包炎,心肌病,心律失常,是发病率和死亡率上升的主要原因。Sars-Cov-2相关心血管疾病的短期和长期预后不仅取决于疾病的严重程度，还取决于相关的疾病和并发症。其中心理健康问题(压力，抑郁和焦虑)有负面影响。SARS-Cov-2感染之间的相互作用，心血管疾病和抑郁症可以解释为过度炎症，不健康的生活方式和器官间的交流，由细胞外囊泡（EV）和非编码microRNA（miRNA）介导。长科维德综合征的特征是体位性低血压，心脏和大脑灌注受损，体位性心动过速综合征（POTS），晕厥,胸痛,呼吸困难,心悸,慢性疲劳综合征,\'脑雾\',记忆,认知和睡眠困难，抑郁和焦虑。从临床观点来看,这些症状可以被认为是不仅代表心脏问题而且代表神经/精神问题的常见症状。因此，对这些症状的评估至关重要。由于其复杂性,这些患者的管理需要多学科护理。
