PDF(Pubmed)
Abstract：
UNASSIGNED: Dilatation of the optic nerve sheath diameter and swelling of the optic disc are known phenomena associated with intracranial pressure elevation.
UNASSIGNED: Do sex and disease etiology have an impact on the development of optic disc elevation and optic nerve sheath extension in children in the setting of ICP elevation? Fundoscopic papilledema and point-of-care-ultrasound techniques-optic nerve sheath diameter (US-ONSD) and optic disc elevation (US-ODE) - were compared in this regard.
UNASSIGNED: 72 children were included in this prospective study; 50 with proven pathology (e.g. pseudotumor cerebri, tumor), 22 with pathology excluded. Bilateral US-ONSD and US-ODE were quantified by US using a 12-MHz-linear-array-transducer. This was compared with fundoscopic optic disc findings and in 28 patients with invasive ICP values, stratified for sex and etiology.
UNASSIGNED: In patients with proven disease, significant more girls (69%) had fundoscopic papilledema compared with boys (37%, p < 0.05). Girls had also larger US-ODE values (0.86 ± 0.36 mm vs. 0.65 ± 0.40 mm in boys). 80% of tumor patients had initial papilledema (100% girls, 79% boys), compared with 50% in pseudotumor cerebri (PTC) (83% girls, 30% boys). US-ONSD had no sex- and no etiology-specificity.
UNASSIGNED: Presence of papilledema appears to be influenced by sex and etiology, whereas US-ONSD is not. Girls seem more likely to develop papilledema under similar conditions. Male sex and PTC appear as risk factors for being undetected by fundoscopic findings. US-ONSD and US-ODE seem useful tools to identify pathologies with potentially increased ICP requiring treatment in children regardless of sex and etiology.
UNASSIGNED: Do sex and disease etiology have an impact on the development of optic disc elevation and optic nerve sheath extension in children in the setting of ICP elevation? Fundoscopic papilledema and point-of-care-ultrasound techniques-optic nerve sheath diameter (US-ONSD) and optic disc elevation (US-ODE) - were compared in this regard.
UNASSIGNED: 72 children were included in this prospective study; 50 with proven pathology (e.g. pseudotumor cerebri, tumor), 22 with pathology excluded. Bilateral US-ONSD and US-ODE were quantified by US using a 12-MHz-linear-array-transducer. This was compared with fundoscopic optic disc findings and in 28 patients with invasive ICP values, stratified for sex and etiology.
UNASSIGNED: In patients with proven disease, significant more girls (69%) had fundoscopic papilledema compared with boys (37%, p < 0.05). Girls had also larger US-ODE values (0.86 ± 0.36 mm vs. 0.65 ± 0.40 mm in boys). 80% of tumor patients had initial papilledema (100% girls, 79% boys), compared with 50% in pseudotumor cerebri (PTC) (83% girls, 30% boys). US-ONSD had no sex- and no etiology-specificity.
UNASSIGNED: Presence of papilledema appears to be influenced by sex and etiology, whereas US-ONSD is not. Girls seem more likely to develop papilledema under similar conditions. Male sex and PTC appear as risk factors for being undetected by fundoscopic findings. US-ONSD and US-ODE seem useful tools to identify pathologies with potentially increased ICP requiring treatment in children regardless of sex and etiology.
摘要：
■视神经鞘直径的扩张和视盘的肿胀是与颅内压升高相关的已知现象。
性别和疾病病因是否会影响ICP抬高儿童视盘抬高和视神经鞘延长的发展？比较了眼底镜下乳头水肿和护理点超声技术-视神经鞘直径（US-ONSD）和视盘抬高（US-ODE）。
■这项前瞻性研究包括72名儿童；50名病理证实的儿童（例如假性脑瘤，肿瘤)，22，病理排除。美国使用12MHz线性阵列传感器对双边US-ONSD和US-ODE进行定量。将其与眼底镜下的视盘检查结果以及28例具有侵入性ICP值的患者进行比较，按性别和病因分层。
■在已证实疾病的患者中，与男孩相比，女孩（69％）有眼底镜视乳头水肿（37％，p<0.05)。女孩的US-ODE值也更大（0.86±0.36毫米与男孩为0.65±0.40mm）。80％的肿瘤患者最初有乳头水肿（100％的女孩，79％的男孩），与假性脑瘤(PTC)的50%相比(83%的女孩，30％的男孩）。US-ONSD没有性别和病因特异性。
■乳头水肿的存在似乎受性别和病因的影响，而美国-ONSD不是。在类似条件下，女孩似乎更有可能发生乳头水肿。男性和PTC似乎是未被眼底镜检查发现的危险因素。US-ONSD和US-ODE似乎是识别具有潜在增加的ICP的病理的有用工具，无论性别和病因如何，儿童都需要治疗。
性别和疾病病因是否会影响ICP抬高儿童视盘抬高和视神经鞘延长的发展？比较了眼底镜下乳头水肿和护理点超声技术-视神经鞘直径（US-ONSD）和视盘抬高（US-ODE）。
■这项前瞻性研究包括72名儿童；50名病理证实的儿童（例如假性脑瘤，肿瘤)，22，病理排除。美国使用12MHz线性阵列传感器对双边US-ONSD和US-ODE进行定量。将其与眼底镜下的视盘检查结果以及28例具有侵入性ICP值的患者进行比较，按性别和病因分层。
■在已证实疾病的患者中，与男孩相比，女孩（69％）有眼底镜视乳头水肿（37％，p<0.05)。女孩的US-ODE值也更大（0.86±0.36毫米与男孩为0.65±0.40mm）。80％的肿瘤患者最初有乳头水肿（100％的女孩，79％的男孩），与假性脑瘤(PTC)的50%相比(83%的女孩，30％的男孩）。US-ONSD没有性别和病因特异性。
■乳头水肿的存在似乎受性别和病因的影响，而美国-ONSD不是。在类似条件下，女孩似乎更有可能发生乳头水肿。男性和PTC似乎是未被眼底镜检查发现的危险因素。US-ONSD和US-ODE似乎是识别具有潜在增加的ICP的病理的有用工具，无论性别和病因如何，儿童都需要治疗。
