Abstract：
Ovarian-type (ie, Mullerian) epithelial tumors occurring in the testicular and paratesticular regions are exceptionally rare, with only a handful reported worldwide. Serous tumors are the most frequently encountered subtype among these rare tumors. The pathogenesis of these tumors within the testicular and paratesticular regions remains a subject of intrigue and debate, with various hypotheses attempting to explain their presence in the paratestis region, where most tumors occur. However, our understanding of the pathogenesis of intratesticular tumors is limited. To date, 11 known examples of intratesticular serous Mullerian tumors have been reported globally. In this report, we present an extraordinary tumor, an intratesticular Mullerian serous borderline tumor with foci of microinvasion, in a 38-year-old male patient. This tumor exhibits histological features similar to their ovarian counterparts and is confirmed through an immunohistochemical panel. Our report underscores the extreme rarity of these tumors, emphasizes the importance of heightened awareness among clinicians and pathologists, and provides valuable insights into their complex development and histogenesis. This contribution aims to enhance diagnostic precision and optimize therapeutic strategies for similar tumors.
摘要：
卵巢型（即，发生在睾丸和睾丸旁区域的Mullerian）上皮肿瘤非常罕见，全球只有少数报道。浆液性肿瘤是这些罕见肿瘤中最常见的亚型。这些肿瘤在睾丸和睾丸旁区域的发病机制仍然是一个有趣和争论的话题。各种假设试图解释它们在paratestis地区的存在，大多数肿瘤发生的地方。然而,我们对睾丸内肿瘤发病机制的理解是有限的。迄今为止,已在全球范围内报道了11种已知的关节内浆液性穆勒肿瘤的例子。在这份报告中,我们展示了一个非同寻常的肿瘤，带微浸润灶的肌膜内浆液性交界性肿瘤，一名38岁的男性患者。该肿瘤表现出与其卵巢对应物相似的组织学特征，并通过免疫组织化学小组得到证实。我们的报告强调了这些肿瘤的极端罕见，强调提高临床医生和病理学家意识的重要性，并提供了对其复杂发展和组织起源的宝贵见解。这一贡献旨在提高诊断精度并优化类似肿瘤的治疗策略。
