OBJECTIVE: To examine the correlation of balloon pressure (BP) during percutaneous microballoon compression (PBC) with postoperative pain relief and complications in the treatment of primary trigeminal neuralgia (PTN).
METHODS: Forty-five patients diagnosed with PTN and treated with PBC were recruited. The BP was recorded at 2 time points: when the balloon achieved the ideal pear shape (initial BP [IBP]) and when the pressure was maintained for 2 min (final BP [FBP]).
METHODS: This study was conducted at the Department of Pain and Rehabilitation of the Second Affiliated Hospital at the University of South China in Hunan, China.
METHODS: The patients\' Barrow Neurological Institute (BNI) pain intensity score, BNI facial numbness score, masticatory muscle weakness score, and recurrence were recorded before and after surgery. The receiver operating characteristic (ROC) curves were generated for the IBP to predict treatment effectiveness, severe facial numbness, and severe masticatory muscle weakness.
RESULTS: The BNI pain intensity score, BNI facial numbness score, and masticatory muscle weakness score were significantly decreased after surgery (all P < 0.001). IBP was positively correlated with the difference between IBP and FBP (P < 0.01). Both IBP and the difference between IBP and FBP were negatively correlated with the BNI pain intensity score and positively correlated with the BNI facial numbness score and masticatory muscle weakness score (P < 0.01). The IBP and the difference between the IBP and FBP were significantly lower in patients experiencing recurrence than in the nonrecurrent group (P < 0.05). The areas under the ROC curves of the IBP for predicting effective pain relief, severe facial numbness, and severe masticatory muscle weakness were 0.875, 0.980, and 0.988, respectively.
CONCLUSIONS: The sample size was relatively small, and the follow-up time was short. The correlations between the BP and other factors, such as filling amount, Meckel\'s cavity, and the size of the foramen ovale, were not investigated. The impact of the BP on long-term postoperative outcomes was not explored.
CONCLUSIONS: An intraoperative BP of 138.65-153.90 KPa can be maintained for effective PBC treatment without causing serious complications.
目的:探讨原发性三叉神经痛(PTN)患者经皮微球囊压迫(PBC)过程中球囊压力(BP)与术后疼痛缓解及并发症的相关性。
方法:纳入45例诊断为PTN并接受PBC治疗的患者。在2个时间点记录BP:当球囊获得理想的梨形状时(初始BP[IBP])和当压力保持2分钟时(最终BP[FBP])。
方法:本研究在湖南南华大学附属第二医院疼痛康复科进行,中国。
方法:患者巴罗神经研究所(BNI)疼痛强度评分,BNI面部麻木评分,咀嚼肌无力评分,记录手术前后的复发情况。为IBP生成受试者工作特征(ROC)曲线以预测治疗效果,严重的面部麻木,和严重的咀嚼肌无力.
结果:BNI疼痛强度评分,BNI面部麻木评分,术后咀嚼肌无力评分明显下降(均P<0.001)。IBP与FBP的差异呈正相关(P<0.01)。IBP及FBP差值均与BNI疼痛强度评分呈负相关,与BNI面部麻木评分、咀嚼肌无力评分呈正相关(P<0.01)。复发患者的IBP以及IBP和FBP之间的差异明显低于未复发组(P<0.05)。预测有效缓解疼痛的IBP的ROC曲线下的面积,严重的面部麻木,严重咀嚼肌无力分别为0.875、0.980和0.988。
结论:样本量相对较小,随访时间很短。BP与其他因素之间的相关性,如填充量,梅克尔的腔,卵圆孔的大小,没有被调查。未探讨BP对术后长期结局的影响。
结论:术中血压维持在138.65-153.90KPa,可有效治疗PBC,不会引起严重并发症。