Abstract：
UNASSIGNED: The comprehensive management of a patient with chronic graft-versus-host disease skin ulcers after hematopoietic stem cell transplantation is challenging. This report describes the case of a 53-year-old woman who presented with ulcers on her right leg 140 weeks after a bone marrow transplant. The patient received wound assessment and management based on the Triangle of Wound Assessment and Wound Bed Preparation 2021, respectively. Hydrogel and antibacterial protease dressings were applied along with systemic oral administration of moxifloxacin hydrochloride (two capsules, two times daily) and JiXueGanPian tablets (classic Chinese herbal formula; two capsules, two times daily), hospital-community-home continuous care, and patient-centered education. Finally, after 133 days of nursing, the patient\'s wound was completely healed without complications or other skin issues. The use of hydrogel combined with the antibacterial protease dressing was a promising technique for handling this type of wound, enhanced by multidisciplinary collaboration. Of course, providing patients with education that focuses on prevention is necessary.
摘要：
造血干细胞移植后患有慢性移植物抗宿主病皮肤溃疡的患者的综合管理具有挑战性。本报告描述了一名53岁妇女在骨髓移植后140周出现右腿溃疡的情况。患者分别基于伤口评估和伤口床准备的三角形2021接受伤口评估和处理。应用水凝胶和抗菌蛋白酶敷料，同时全身口服盐酸莫西沙星（两粒胶囊，每日两次)和鸡血肝片(中草药经典配方；两种胶囊，每天两次)，医院-社区-家庭持续护理，以病人为中心的教育。最后,经过133天的护理，患者的伤口完全愈合，没有并发症或其他皮肤问题。水凝胶与抗菌蛋白酶敷料的结合使用是处理此类伤口的有前途的技术，通过多学科合作得到加强。当然,为患者提供以预防为重点的教育是必要的。
