PDF(Pubmed)
Abstract：
Polymorphous low-grade adenocarcinoma (PLGA) is a rare neoplasm with an indolent course that occurs mainly in minor salivary glands and rarely in major salivary glands. It is characterised by morphological diversity hence the term polymorphous has been used. Diagnosis is often challenging due to variable microscopic growth patterns. The most common clinical presentation is asymptomatic painless mass which is slow growing. The treatment of choice is wide surgical excision with negative margins. The role of radiotherapy is still not clear but considered in cases with positive margins and advanced stage. In this article, we review the clinical presentation, pathological features, treatment, and prognosis of this rare entity.
摘要：
多形性低度腺癌（PLGA）是一种罕见的肿瘤，病程缓慢，主要发生在小唾液腺中，很少发生在大唾液腺中。其特征在于形态多样性,因此使用术语多态。由于微观生长模式的变化，诊断通常具有挑战性。最常见的临床表现是无症状的无痛性肿块，其生长缓慢。选择的治疗方法是广泛的手术切除，切缘阴性。放疗的作用尚不清楚，但在切缘阳性和晚期的病例中考虑。在这篇文章中,我们回顾了临床表现，病理特征,治疗,以及这种罕见实体的预后。
