PDF(Pubmed)
Abstract：
UNASSIGNED: Our aim was to investigate the relationship between chronic kidney disease (CKD) duration and suicide risk among maintenance hemodialysis patients in China.
UNASSIGNED: Patients with end-stage renal disease (ESRD) who received MHD were enrolled. The demographic and disease characteristics of MHD patients were collected using a self-designed basic information questionnaire. The Suicide Risk Assessment Scale was used to assess suicide risk.
UNASSIGNED: A total of 543 (40.8%) patients had suicide risk with Nurses\' Global Assessment Scale for Suicide Risk scores ranging from 1 to 19 points. After adjusting for age, gender, disease conditions and mental state, the odds ratios of different CKD duration for suicide risk were 1.00, 2.02, 3.03 and 2.71, respectively (P for trend <.001). There were significant interactions between CKD duration and ESRD duration in relation to suicide risk (P for interaction <.001). There were also interactions between CKD duration and hemodialysis treatment duration, and suicide risk (P for interaction = .01). Patients with ESRD duration of ≤28 months or hemodialysis treatment duration of ≤24 months had the highest risk of suicide when the duration of CKD was 63-94 months, about 2-10 times higher than the other time groups.
UNASSIGNED: We found that CKD duration was associated with an increased risk of suicide in maintenance hemodialysis patients in China, independently of other risk factors. Early ESRD and maintenance hemodialysis were associated with suicide in CKD patients.
UNASSIGNED: Patients with end-stage renal disease (ESRD) who received MHD were enrolled. The demographic and disease characteristics of MHD patients were collected using a self-designed basic information questionnaire. The Suicide Risk Assessment Scale was used to assess suicide risk.
UNASSIGNED: A total of 543 (40.8%) patients had suicide risk with Nurses\' Global Assessment Scale for Suicide Risk scores ranging from 1 to 19 points. After adjusting for age, gender, disease conditions and mental state, the odds ratios of different CKD duration for suicide risk were 1.00, 2.02, 3.03 and 2.71, respectively (P for trend <.001). There were significant interactions between CKD duration and ESRD duration in relation to suicide risk (P for interaction <.001). There were also interactions between CKD duration and hemodialysis treatment duration, and suicide risk (P for interaction = .01). Patients with ESRD duration of ≤28 months or hemodialysis treatment duration of ≤24 months had the highest risk of suicide when the duration of CKD was 63-94 months, about 2-10 times higher than the other time groups.
UNASSIGNED: We found that CKD duration was associated with an increased risk of suicide in maintenance hemodialysis patients in China, independently of other risk factors. Early ESRD and maintenance hemodialysis were associated with suicide in CKD patients.
摘要：
■我们的目的是调查中国维持性血液透析患者的慢性肾脏病（CKD）持续时间与自杀风险之间的关系。
■纳入接受MHD的终末期肾病（ESRD）患者。使用自行设计的基本信息问卷收集MHD患者的人口统计学和疾病特征。自杀风险评估量表用于评估自杀风险。
■共有543名（40.8%）患者有自杀风险，护士全球自杀风险评估量表评分为1至19分。在调整了年龄之后,性别,疾病状况和精神状态，不同CKD持续时间对自杀风险的比值比分别为1.00,2.02,3.03和2.71(趋势P<.001).CKD持续时间和ESRD持续时间与自杀风险之间存在显著的交互作用(P表示交互作用<.001)。CKD持续时间和血液透析治疗持续时间之间也存在相互作用，和自杀风险（相互作用的P=0.01）。当CKD持续时间为63-94个月时，ESRD持续时间≤28个月或血液透析治疗持续时间≤24个月的患者自杀风险最高。大约比其他时间组高2-10倍。
■我们发现，中国维持性血液透析患者的CKD持续时间与自杀风险增加有关，独立于其他风险因素。早期ESRD和维持性血液透析与CKD患者自杀有关。
■纳入接受MHD的终末期肾病（ESRD）患者。使用自行设计的基本信息问卷收集MHD患者的人口统计学和疾病特征。自杀风险评估量表用于评估自杀风险。
■共有543名（40.8%）患者有自杀风险，护士全球自杀风险评估量表评分为1至19分。在调整了年龄之后,性别,疾病状况和精神状态，不同CKD持续时间对自杀风险的比值比分别为1.00,2.02,3.03和2.71(趋势P<.001).CKD持续时间和ESRD持续时间与自杀风险之间存在显著的交互作用(P表示交互作用<.001)。CKD持续时间和血液透析治疗持续时间之间也存在相互作用，和自杀风险（相互作用的P=0.01）。当CKD持续时间为63-94个月时，ESRD持续时间≤28个月或血液透析治疗持续时间≤24个月的患者自杀风险最高。大约比其他时间组高2-10倍。
■我们发现，中国维持性血液透析患者的CKD持续时间与自杀风险增加有关，独立于其他风险因素。早期ESRD和维持性血液透析与CKD患者自杀有关。
