Abstract：
Vulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget\'s disease, Bartholin gland adenocarcinoma, verrucous carcinoma, basal cell carcinoma, and sarcoma. This manuscript discusses recommendations outlined in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for treatments, surveillance, systemic therapy options, and gynecologic survivorship.
摘要：
每年在估计的6,470个人中诊断外阴癌,并且绝大多数是组织学鳞状细胞癌。外阴癌占妇科恶性肿瘤的5％至8％。外阴癌的已知危险因素包括年龄增加，人乳头瘤病毒感染，吸烟,影响外阴的炎症，和免疫缺陷。大多数外阴新生在早期被诊断。存在较少组织学，包括黑色素瘤，乳房外Paget病,前庭大腺腺癌，疣状癌,基底细胞癌,和肉瘤.本手稿讨论了NCCN肿瘤学临床实践指南（NCCN指南）中概述的治疗建议，监视,全身治疗方案,和妇科幸存者。
