关键词: Abscess Fusobacterium Liver Liver abscess Pyogenic liver abcess

来  源:   DOI:10.1159/000536619   PDF(Pubmed)

Abstract:
UNASSIGNED: Pyogenic liver abscess is a noteworthy health concern in North America, characterized by a mortality rate ranging from 2 to 12%. This condition is often polymicrobial, with Streptococcus species and Escherichia coli as the predominant causal pathogens in Western countries. Fusobacterium species, typically commensals of gastrointestinal, genital, and oral flora, have been implicated in the rare formation of tonsillar abscesses and Lemierre syndrome, including its gastrointestinal variant known as pylephlebitis.
UNASSIGNED: We present the case of an immunocompetent male with a 2-week history of abdominal distention and pain. Abdominal magnetic resonance imaging revealed multiseptated cystic hepatic masses and portal vein thrombosis. A subsequent liver biopsy confirmed Fusobacterium nucleatum etiology. The patient was initiated on intravenous cefepime and oral metronidazole antibiotics. Unfortunately, the patient succumbed to cardiac arrest before a final diagnosis could be established.
UNASSIGNED: Fusobacterium species-associated liver abscess, coupled with the rare gastrointestinal variant of Lemierre syndrome (pylephlebitis), poses a significant mortality risk. This case underscores the rarity and clinical challenges associated with these conditions. Increased awareness among clinicians is crucial for early diagnosis and prompt intervention, potentially improving outcomes in such cases.
摘要:
化脓性肝脓肿在北美是一个值得注意的健康问题,其特征是死亡率从2%到12%不等。这种情况通常是多微生物的,在西方国家,以链球菌和大肠杆菌为主要病原。梭杆菌属物种,通常是胃肠道的共生体,生殖器,和口腔菌群,与罕见的扁桃体脓肿和Lemierre综合征有关,包括它的胃肠变种称为静脉炎。
我们介绍了一个有2周腹胀和疼痛史的免疫功能正常的男性病例。腹部磁共振成像显示多间隔囊性肝肿块和门静脉血栓形成。随后的肝活检证实了核梭杆菌的病因。患者开始静脉注射头孢吡肟和口服甲硝唑抗生素。不幸的是,患者在最终诊断之前死于心脏骤停.
梭杆菌属物种相关肝脓肿,再加上罕见的Lemierre综合征(静脉炎)的胃肠道变异,会带来巨大的死亡风险。该病例强调了与这些病症相关的罕见性和临床挑战。提高临床医生的认识对于早期诊断和及时干预至关重要。在这种情况下可能会改善结果。
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