T 细胞活化有助于针对血液中 MELAS 相关的 m.3243 A > G 致病变体的纯化选择。
关键词: MELAS MIDD T cell activation heteroplasmy mitochondria mtDNA
Mesh : Humans MELAS Syndrome / genetics Lymphocyte Activation CD4-Positive T-Lymphocytes / immunology Heteroplasmy / genetics RNA, Transfer, Leu / genetics Male Female DNA, Mitochondrial / genetics Adult
来 源:
DOI:10.1002/jimd.12726
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