Abstract：
BACKGROUND: Lung tumors are prevalent malignancies associated with a high mortality rate, imposing significant medical and societal burdens. Although immunotherapy shows promise in improving survival, response rates are relatively modest. Thermal ablation can not only eliminate tumor cells directly but also enhance antitumor immunity response, thus manifesting a remarkable propensity to synergize with immunotherapy.
CONCLUSIONS: In this review, we provided a brief overview of the application of thermal ablation in peripheral lung tumors. We summarized the patient selection of thermal ablation. We highlighted the potential of thermal ablation to augment the antitumor immune response, offering a promising avenue for combined therapies. We summarized studies assessing the synergistic effects of thermal ablation and immunotherapy in preclinical and clinical settings. Lastly, we underscored the urgent issues that warrant in-depth exploration when applying thermal ablation and immunotherapy to lung tumor patients.
CONCLUSIONS: This review emphasized the prospects of using thermal ablation combined with immunotherapy in patients with peripheral lung tumors. However, further research is needed to enhance and optimize this treatment strategy.
CONCLUSIONS: In this review, we provided a brief overview of the application of thermal ablation in peripheral lung tumors. We summarized the patient selection of thermal ablation. We highlighted the potential of thermal ablation to augment the antitumor immune response, offering a promising avenue for combined therapies. We summarized studies assessing the synergistic effects of thermal ablation and immunotherapy in preclinical and clinical settings. Lastly, we underscored the urgent issues that warrant in-depth exploration when applying thermal ablation and immunotherapy to lung tumor patients.
CONCLUSIONS: This review emphasized the prospects of using thermal ablation combined with immunotherapy in patients with peripheral lung tumors. However, further research is needed to enhance and optimize this treatment strategy.
摘要：
背景：肺肿瘤是与高死亡率相关的常见恶性肿瘤，造成重大的医疗和社会负担。尽管免疫疗法显示出改善生存率的希望，反应率相对适中。热消融不仅可以直接消除肿瘤细胞，还可以增强抗肿瘤免疫反应，因此表现出与免疫治疗协同作用的显著倾向。
结论：在这篇综述中，我们简要概述了热消融在周围型肺肿瘤中的应用.我们总结了热消融的患者选择。我们强调了热消融增强抗肿瘤免疫反应的潜力，为联合疗法提供了一个有希望的途径。我们总结了评估热消融和免疫治疗在临床前和临床环境中的协同作用的研究。最后,我们强调了在将热消融和免疫疗法应用于肺部肿瘤患者时需要深入探索的紧迫问题.
结论：这篇综述强调了在周围型肺肿瘤患者中使用热消融联合免疫治疗的前景。然而,需要进一步的研究来加强和优化这种治疗策略.
结论：在这篇综述中，我们简要概述了热消融在周围型肺肿瘤中的应用.我们总结了热消融的患者选择。我们强调了热消融增强抗肿瘤免疫反应的潜力，为联合疗法提供了一个有希望的途径。我们总结了评估热消融和免疫治疗在临床前和临床环境中的协同作用的研究。最后,我们强调了在将热消融和免疫疗法应用于肺部肿瘤患者时需要深入探索的紧迫问题.
结论：这篇综述强调了在周围型肺肿瘤患者中使用热消融联合免疫治疗的前景。然而,需要进一步的研究来加强和优化这种治疗策略.
