Abstract：
OBJECTIVE: To evaluate the predictive factors of tumor growth in patients with vestibular schwannoma (VS) managed with the wait-and-scan approach.
METHODS: The data of 31 patients diagnosed with intracanalicular VS and followed for > 5 years were retrospectively analyzed. VS was diagnosed according to MRI findings and tumor growth was monitored. Tumor growth was defined as an increase of 2 mm or more in the maximal tumor diameter. The association between the initial tumor size and shape and tumor growth was assessed.
RESULTS: Tumor growth was observed in 16 of 31 patients (51.6%) over a mean follow-up duration of 7.3 years. The initial tumor size was not statistically correlated with tumor growth. However, fusiform or cylindrical tumors exhibited higher growth rates than oval or round tumors. Additionally, a significant correlation was observed between cerebellopontine angle extension and tumor shape.
CONCLUSIONS: In this study, 51.6% of the patients with intracanalicular VS who were managed with the wait-and-scan strategy over a follow-up period of > 5 years showed tumor growth. Tumor shape, especially fusiform or cylindrical shape, was found to be a significant predictor of tumor growth.
METHODS: The data of 31 patients diagnosed with intracanalicular VS and followed for > 5 years were retrospectively analyzed. VS was diagnosed according to MRI findings and tumor growth was monitored. Tumor growth was defined as an increase of 2 mm or more in the maximal tumor diameter. The association between the initial tumor size and shape and tumor growth was assessed.
RESULTS: Tumor growth was observed in 16 of 31 patients (51.6%) over a mean follow-up duration of 7.3 years. The initial tumor size was not statistically correlated with tumor growth. However, fusiform or cylindrical tumors exhibited higher growth rates than oval or round tumors. Additionally, a significant correlation was observed between cerebellopontine angle extension and tumor shape.
CONCLUSIONS: In this study, 51.6% of the patients with intracanalicular VS who were managed with the wait-and-scan strategy over a follow-up period of > 5 years showed tumor growth. Tumor shape, especially fusiform or cylindrical shape, was found to be a significant predictor of tumor growth.
摘要：
目的：评估前庭神经鞘瘤（VS）患者的肿瘤生长的预测因素。
方法：对31例诊断为小管内VS并随访5年以上的患者资料进行回顾性分析。根据MRI结果诊断VS并监测肿瘤生长。肿瘤生长定义为最大肿瘤直径增加2mm或更多。评估初始肿瘤大小和形状与肿瘤生长之间的关联。
结果：在平均7.3年的随访时间内，31例患者中有16例（51.6%）观察到肿瘤生长。初始肿瘤大小与肿瘤生长无统计学相关。然而,梭形或圆柱形肿瘤的生长速率高于椭圆形或圆形肿瘤。此外,观察到桥小脑角延伸与肿瘤形状之间存在显着相关性。
结论：在这项研究中，在>5年的随访期内，通过等待和扫描策略进行管理的51.6％的小管内VS患者显示出肿瘤生长。肿瘤形状,尤其是梭形或圆柱形，被发现是肿瘤生长的重要预测因子。
方法：对31例诊断为小管内VS并随访5年以上的患者资料进行回顾性分析。根据MRI结果诊断VS并监测肿瘤生长。肿瘤生长定义为最大肿瘤直径增加2mm或更多。评估初始肿瘤大小和形状与肿瘤生长之间的关联。
结果：在平均7.3年的随访时间内，31例患者中有16例（51.6%）观察到肿瘤生长。初始肿瘤大小与肿瘤生长无统计学相关。然而,梭形或圆柱形肿瘤的生长速率高于椭圆形或圆形肿瘤。此外,观察到桥小脑角延伸与肿瘤形状之间存在显着相关性。
结论：在这项研究中，在>5年的随访期内，通过等待和扫描策略进行管理的51.6％的小管内VS患者显示出肿瘤生长。肿瘤形状,尤其是梭形或圆柱形，被发现是肿瘤生长的重要预测因子。
