PDF(Pubmed)
Abstract：
UNASSIGNED: Dietary temperance significantly affects the quality of life of patients with Crohn\'s disease (CD) and remains a major concern. However, perceptions of diet in remission may have changed from the era when treatment options were limited. Therefore, we compared the dietary perceptions and treatment of patients with CD in remission with previously published data from the time biologic therapy was not introduced.
UNASSIGNED: We compared the data of 254 patients with CD in remission who completed a questionnaire survey in 2022 with those of 76 patients with CD in remission collected in 2003, when biologics were not used for maintenance therapy in Japan. Remission was defined as a CD activity index of 150 or less in both studies. Perceptions of diet (degree of eating whatever one likes) were assessed using single-item nominal scale responses.
UNASSIGNED: The percentage of patients receiving enteral nutrition therapy had decreased (past vs. present: 43.4 vs. 12.6%), while the proportion of patients receiving biologic therapy increased (0 vs. 88.6%, respectively). The percentages of patients who responded \"not at all,\" \"sometimes,\" and \"mostly\" when asked if they could eat whatever they liked had changed, respectively, from 9.2%, 46.1%, and 44.7% in the past to 4.3%, 25.2%, and 70.5% in the present.
UNASSIGNED: The proportion of those who ate whatever they liked and the mean body mass index increased in comparison with the corresponding values 20 years ago. With the advent of biologic therapies, the number of patients with CD who can enjoy eating has increased.
UNASSIGNED: We compared the data of 254 patients with CD in remission who completed a questionnaire survey in 2022 with those of 76 patients with CD in remission collected in 2003, when biologics were not used for maintenance therapy in Japan. Remission was defined as a CD activity index of 150 or less in both studies. Perceptions of diet (degree of eating whatever one likes) were assessed using single-item nominal scale responses.
UNASSIGNED: The percentage of patients receiving enteral nutrition therapy had decreased (past vs. present: 43.4 vs. 12.6%), while the proportion of patients receiving biologic therapy increased (0 vs. 88.6%, respectively). The percentages of patients who responded \"not at all,\" \"sometimes,\" and \"mostly\" when asked if they could eat whatever they liked had changed, respectively, from 9.2%, 46.1%, and 44.7% in the past to 4.3%, 25.2%, and 70.5% in the present.
UNASSIGNED: The proportion of those who ate whatever they liked and the mean body mass index increased in comparison with the corresponding values 20 years ago. With the advent of biologic therapies, the number of patients with CD who can enjoy eating has increased.
摘要：
■饮食节制显着影响克罗恩病（CD）患者的生活质量，并且仍然是一个主要问题。然而,从治疗选择有限的时代开始,人们对缓解期饮食的看法可能已经改变.因此,我们将缓解期CD患者的饮食观念和治疗与未采用生物治疗时以前发表的数据进行了比较.
■我们比较了2022年完成问卷调查的254例缓解期CD患者与2003年收集的76例缓解期CD患者的数据，当时生物制剂未用于日本的维持治疗。在两项研究中，缓解被定义为CD活性指数为150或更低。使用单项目标称量表响应评估饮食的感知（喜欢吃什么的程度）。
■接受肠内营养治疗的患者百分比下降（过去与目前：43.4vs.12.6%），而接受生物治疗的患者比例增加(0vs.88.6%,分别)。回答“根本没有”的患者百分比，\"\"有时,当被问及他们是否可以吃任何他们喜欢的东西时，分别,从9.2%，46.1%,从过去的44.7%到4.3%，25.2%,和目前的70.5%。
■与20年前的相应值相比，那些喜欢吃什么的人的比例和平均体重指数增加了。随着生物疗法的出现，可以享受饮食的CD患者数量有所增加。
■我们比较了2022年完成问卷调查的254例缓解期CD患者与2003年收集的76例缓解期CD患者的数据，当时生物制剂未用于日本的维持治疗。在两项研究中，缓解被定义为CD活性指数为150或更低。使用单项目标称量表响应评估饮食的感知（喜欢吃什么的程度）。
■接受肠内营养治疗的患者百分比下降（过去与目前：43.4vs.12.6%），而接受生物治疗的患者比例增加(0vs.88.6%,分别)。回答“根本没有”的患者百分比，\"\"有时,当被问及他们是否可以吃任何他们喜欢的东西时，分别,从9.2%，46.1%,从过去的44.7%到4.3%，25.2%,和目前的70.5%。
■与20年前的相应值相比，那些喜欢吃什么的人的比例和平均体重指数增加了。随着生物疗法的出现，可以享受饮食的CD患者数量有所增加。
