PDF(Pubmed)
Abstract：
Mycosis fungoides (MF) is the most common primary cutaneous T-cell lymphoma with a usually indolent course. Early detection is crucial for effective intervention. We present a case of a 40-year-old male with MF exhibiting blistering as a rare precursor symptom. Despite initial treatment for eczema, the condition worsened over 10 months, leading to erythema, edema, and enlarged lymph nodes. Laboratory and imaging findings confirmed the diagnosis of MF. The patient responded partially to cyclophosphamide/doxorubicin/prednisone in combination with brentuximab vedotin (A-CHP) therapy. This case highlights the significance of recognizing blistering as a prodromal symptom for early detection and management of MF.
摘要：
真菌肉芽肿（MF）是最常见的原发性皮肤T细胞淋巴瘤，通常病程缓慢。早期发现对于有效干预至关重要。我们介绍了一例40岁的男性，MF表现出起泡是一种罕见的前兆症状。尽管最初治疗湿疹，病情恶化超过10个月，导致红斑,水肿,淋巴结肿大.实验室和影像学检查结果证实了MF的诊断。患者对环磷酰胺/多柔比星/泼尼松联合本妥昔单抗维多丁（A-CHP）治疗部分反应。此病例凸显了将起泡识别为前驱症状对于MF的早期发现和管理的重要性。
