PDF(Pubmed)
Abstract：
UNASSIGNED: Rickettsia japonica infection is a rare disease, it is rare to report critical and severe case caused by this disease in Zhejiang Province, China.
UNASSIGNED: We report a patient who initially sought medical attention due to fever and developed coma and convulsions during treatment. The patient did not develop typical eschar and rash. Eventually, the patient needed to be treated in the intensive care unit due to acute respiratory failure.
UNASSIGNED: The patient was diagnosed with Rickettsia japonica bloodstream infection by metagenomic next-generation sequencing (mNGS).
UNASSIGNED: Due to the critical illness, the patient was transferred to the intensive care unit, received doxycycline and other treatments, and rapidly recovered and discharged.
UNASSIGNED: The patient developed a critical illness after being infected with Rickettsia, when the medical history is unclear and clinical symptoms and signs are atypical, it is necessary to use mNGS examination for diagnosis.
UNASSIGNED: We report a patient who initially sought medical attention due to fever and developed coma and convulsions during treatment. The patient did not develop typical eschar and rash. Eventually, the patient needed to be treated in the intensive care unit due to acute respiratory failure.
UNASSIGNED: The patient was diagnosed with Rickettsia japonica bloodstream infection by metagenomic next-generation sequencing (mNGS).
UNASSIGNED: Due to the critical illness, the patient was transferred to the intensive care unit, received doxycycline and other treatments, and rapidly recovered and discharged.
UNASSIGNED: The patient developed a critical illness after being infected with Rickettsia, when the medical history is unclear and clinical symptoms and signs are atypical, it is necessary to use mNGS examination for diagnosis.
摘要：
■日本立克次体感染是一种罕见的疾病，在浙江省，这种疾病引起的危重病例很少见，中国。
■我们报告了一名最初因发烧求医的患者，在治疗期间出现昏迷和抽搐。患者未出现典型的焦痂和皮疹。最终,由于急性呼吸衰竭，患者需要在重症监护病房接受治疗。
■患者通过宏基因组下一代测序（mNGS）诊断为日本立克次体血流感染。
■由于病情危重,病人被转移到重症监护室,接受多西环素和其他治疗，迅速康复出院。
■患者感染立克次体后患上了危重疾病，当病史不明确且临床症状和体征不典型时，有必要使用mNGS检查进行诊断。
■我们报告了一名最初因发烧求医的患者，在治疗期间出现昏迷和抽搐。患者未出现典型的焦痂和皮疹。最终,由于急性呼吸衰竭，患者需要在重症监护病房接受治疗。
■患者通过宏基因组下一代测序（mNGS）诊断为日本立克次体血流感染。
■由于病情危重,病人被转移到重症监护室,接受多西环素和其他治疗，迅速康复出院。
■患者感染立克次体后患上了危重疾病，当病史不明确且临床症状和体征不典型时，有必要使用mNGS检查进行诊断。
