Abstract：
OBJECTIVE: Immunocompromised B-cell-depleted patients are at risk of developing protracted COVID-19, a clinical syndrome characterized by prolonged viral shedding and respiratory symptoms that can lead to hypoxemic pneumonia. Our aim is to describe this unusual condition and its treatment.
METHODS: This monocentric retrospective study reports six cases of severe organizing pneumonia that developed during the clinical course of protracted COVID-19.
RESULTS: All patients developed organizing pneumonia (OP) in the setting of protracted COVID. Clinical improvement was obtained after several treatment lines including specific antiviral agents and occurred simultaneously with control of the viral load.
CONCLUSIONS: As it was the most frequent presentation of protracted COVID-19 in our survey, we believe that this specific form of organizing pneumonia warrants increased awareness. Furthermore, specific antiviral therapy seems to control this condition.
METHODS: This monocentric retrospective study reports six cases of severe organizing pneumonia that developed during the clinical course of protracted COVID-19.
RESULTS: All patients developed organizing pneumonia (OP) in the setting of protracted COVID. Clinical improvement was obtained after several treatment lines including specific antiviral agents and occurred simultaneously with control of the viral load.
CONCLUSIONS: As it was the most frequent presentation of protracted COVID-19 in our survey, we believe that this specific form of organizing pneumonia warrants increased awareness. Furthermore, specific antiviral therapy seems to control this condition.
摘要：
目的：免疫功能低下的B细胞耗竭患者有发展为持续性COVID-19的风险，COVID-19是一种临床综合征，其特征是病毒长时间脱落和呼吸道症状，可导致低氧血症肺炎。我们的目的是描述这种异常情况及其治疗方法。
方法：这项单中心回顾性研究报告了6例严重的机化性肺炎，这些肺炎在COVID-19的临床过程中发生。
结果：所有患者都在长期COVID环境中发展为机化性肺炎（OP）。在包括特定抗病毒剂在内的几种治疗线后获得了临床改善，并且与病毒载量的控制同时发生。
结论：由于这是我们调查中最常见的持续性COVID-19，我们认为，这种特定形式的组织肺炎需要提高认识。此外，特定的抗病毒治疗似乎可以控制这种情况。
方法：这项单中心回顾性研究报告了6例严重的机化性肺炎，这些肺炎在COVID-19的临床过程中发生。
结果：所有患者都在长期COVID环境中发展为机化性肺炎（OP）。在包括特定抗病毒剂在内的几种治疗线后获得了临床改善，并且与病毒载量的控制同时发生。
结论：由于这是我们调查中最常见的持续性COVID-19，我们认为，这种特定形式的组织肺炎需要提高认识。此外，特定的抗病毒治疗似乎可以控制这种情况。
