Abstract：
BACKGROUND: The aim of this study was to investigate the efficacy of new monofocal intraocular lens (IOL) in comparison with conventional monofocal IOL in patients undergoing combined cataract and vitrectomy surgery for epiretinal membrane (ERM).
METHODS: This prospective non-randomized comparative study included 65 eyes of 65 patients who underwent combined cataract and vitrectomy for ERM with implantation of advanced monofocal IOL (Eyhance ICB00, 33 patients) and standard monofocal IOL (Tecnis ZCB00, 32 patients). Monocular visual acuities were measured 6 months post-operatively, including corrected and uncorrected distance visual acuity (CDVA, UCDVA), uncorrected intermediate visual acuity (UCIVA), and uncorrected near visual acuity (UCNVA). Furthermore, contrast sensitivity and metamorphopsia were measured.
RESULTS: There was no significant difference between two groups regarding operation time, post-operative CDVA, UCDVA, UCNVA, and spherical equivalent (p > 0.05). Monocular UCIVA was significantly higher in the Eyhance IOL group than in the Tecnis IOL group (p = 0.005). The photopic and mesopic contrast sensitivities were comparable between each group for any spatial frequency (p > 0.05). The correlation coefficients from correlations between retinal wrinkling ratio and M score did not differ significantly between groups (p = 0.877), and the degree of metamorphopsia was not significantly related to the type of IOL (p = 0.969).
CONCLUSIONS: In combined cataract and vitrectomy for ERM, Eyhance IOL provided significant better visual performance at intermediate distance than standard monofocal IOL without compromising operation time, distance vision, contrast sensitivity, and evaluating metamorphopsia. Eyhance IOL can be a useful option for both surgeons and patients.
METHODS: This prospective non-randomized comparative study included 65 eyes of 65 patients who underwent combined cataract and vitrectomy for ERM with implantation of advanced monofocal IOL (Eyhance ICB00, 33 patients) and standard monofocal IOL (Tecnis ZCB00, 32 patients). Monocular visual acuities were measured 6 months post-operatively, including corrected and uncorrected distance visual acuity (CDVA, UCDVA), uncorrected intermediate visual acuity (UCIVA), and uncorrected near visual acuity (UCNVA). Furthermore, contrast sensitivity and metamorphopsia were measured.
RESULTS: There was no significant difference between two groups regarding operation time, post-operative CDVA, UCDVA, UCNVA, and spherical equivalent (p > 0.05). Monocular UCIVA was significantly higher in the Eyhance IOL group than in the Tecnis IOL group (p = 0.005). The photopic and mesopic contrast sensitivities were comparable between each group for any spatial frequency (p > 0.05). The correlation coefficients from correlations between retinal wrinkling ratio and M score did not differ significantly between groups (p = 0.877), and the degree of metamorphopsia was not significantly related to the type of IOL (p = 0.969).
CONCLUSIONS: In combined cataract and vitrectomy for ERM, Eyhance IOL provided significant better visual performance at intermediate distance than standard monofocal IOL without compromising operation time, distance vision, contrast sensitivity, and evaluating metamorphopsia. Eyhance IOL can be a useful option for both surgeons and patients.
摘要：
背景：本研究的目的是研究新型单焦点人工晶状体（IOL）与常规单焦点人工晶状体（IOL）在接受白内障和玻璃体切除术联合手术治疗视网膜前膜（ERM）的患者中的疗效。
方法：这项前瞻性非随机对照研究包括65例接受白内障和玻璃体切除术联合治疗ERM并植入晚期单焦点IOL（EyhanceICB00，33例）和标准单焦点IOL（TecnisZCB00，32例）的患者的65只眼。术后6个月测量单眼视力，包括矫正视力和未矫正视力(CDVA，UCDVA)，未矫正视力（UCIVA），和未矫正的近视敏度（UCNVA）。此外，测量对比敏感度和变形视。
结果：两组手术时间无明显差异，术后CDVA,UCDVA,UCNVA,和球形当量(p>0.05)。EyhanceIOL组的单眼UCIVA明显高于TecnisIOL组（p=0.005）。对于任何空间频率，每组之间的明视和中视对比敏感度均相当（p＆gt;0.05）。视网膜皱纹率与M评分之间的相关系数在各组之间没有显着差异（p=0.877），变形程度与IOL类型无关(p=0.969)。
结论：在合并白内障和玻璃体切除术治疗ERM中，EyhanceIOL在中等距离比标准单焦点IOL提供了明显更好的视觉性能，而不影响手术时间，远距视觉,对比敏感度,并评估变形视。EyhanceIOL对于外科医生和患者都是有用的选择。
方法：这项前瞻性非随机对照研究包括65例接受白内障和玻璃体切除术联合治疗ERM并植入晚期单焦点IOL（EyhanceICB00，33例）和标准单焦点IOL（TecnisZCB00，32例）的患者的65只眼。术后6个月测量单眼视力，包括矫正视力和未矫正视力(CDVA，UCDVA)，未矫正视力（UCIVA），和未矫正的近视敏度（UCNVA）。此外，测量对比敏感度和变形视。
结果：两组手术时间无明显差异，术后CDVA,UCDVA,UCNVA,和球形当量(p>0.05)。EyhanceIOL组的单眼UCIVA明显高于TecnisIOL组（p=0.005）。对于任何空间频率，每组之间的明视和中视对比敏感度均相当（p＆gt;0.05）。视网膜皱纹率与M评分之间的相关系数在各组之间没有显着差异（p=0.877），变形程度与IOL类型无关(p=0.969)。
结论：在合并白内障和玻璃体切除术治疗ERM中，EyhanceIOL在中等距离比标准单焦点IOL提供了明显更好的视觉性能，而不影响手术时间，远距视觉,对比敏感度,并评估变形视。EyhanceIOL对于外科医生和患者都是有用的选择。
