Abstract：
Electrospinning has been acknowledged as an efficient technique for the fabrication of continuous nanofibers from polymeric based materials such as polyvinyl alcohol (PVA), cellulose acetate (CA), chitin nanocrystals and others. These nanofibers exhibit chemical and mechanical stability, high porosity, functionality, high surface area and one-dimensional orientation which make it extremely beneficial in industrial application. In recent years, research on chitin - a biopolymer derived from crustacean and fungal cell wall - had gained interest due to its unique structural arrangement, excellent physical and chemical properties, in which make it biodegradable, non-toxic and biocompatible. Chitin has been widely utilized in various applications such as wound dressings, drug delivery, tissue engineering, membranes, food packaging and others. However, chitin is insoluble in most solvents due to its highly crystalline structure. An appropriate solvent system is required for dissolving chitin to maximize its application and produce a fine and smooth electrospun nanofiber. This review focuses on the preparation of chitin polymer solution through dissolution process using different types of solvent system for electrospinning process. The effect of processing parameters also discussed by highlighting some representative examples. Finally, the perspectives are presented regarding the current application of electrospun chitin nanofibers in selected fields.
摘要：
静电纺丝已被公认为一种有效的技术，用于从基于聚合物的材料如聚乙烯醇（PVA）制造连续的纳米纤维，醋酸纤维素(CA),几丁质纳米晶体和其他。这些纳米纤维表现出化学和机械稳定性，高孔隙率,功能，高表面积和一维取向，使其在工业应用中极为有利。近年来,甲壳素-一种源自甲壳类和真菌细胞壁的生物聚合物-的研究由于其独特的结构排列而引起了人们的兴趣，优异的物理和化学性质，使其可生物降解，无毒和生物相容性。几丁质已广泛用于各种应用，如伤口敷料，药物输送,组织工程,膜，食品包装等。然而,几丁质由于其高度的结晶结构而不溶于大多数溶剂。需要适当的溶剂体系来溶解几丁质以最大化其应用并产生精细和光滑的电纺纳米纤维。本文重点介绍了通过溶解过程使用不同类型的溶剂体系制备甲壳素聚合物溶液的方法。还通过突出一些代表性实例讨论了加工参数的影响。最后,介绍了静电纺甲壳素纳米纤维在选定领域的应用现状。
