关键词: Case report Chorea Depression Huntington disease Repetitive transcranial magnetic stimulation

来  源:   DOI:10.1159/000537750   PDF(Pubmed)

Abstract:
UNASSIGNED: Huntington disease (HD) is a progressive disorder characterized by significant neurodegeneration that results in severe neuropsychiatric symptoms and disordered movement. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive treatment that has been used in major depressive disorder (MDD) with great success.
UNASSIGNED: We present a case of a patient with newly diagnosed HD, persistent MDD with suicidal ideation, and generalized anxiety disorder who was treated with rTMS and had sustained significant improvement of her mood disorder with additional improvement of her movement disorder.
UNASSIGNED: This result brings into question the use of rTMS to treat MDD and chorea in patients with HD, especially early in its course.
摘要:
亨廷顿病(HD)是一种进行性疾病,其特征在于显著的神经变性,其导致严重的神经精神症状和紊乱的运动。重复经颅磁刺激(rTMS)是一种无创治疗方法,已成功用于重度抑郁症(MDD)。
我们介绍了一个新诊断为HD的患者,有自杀意念的持续性MDD,和广泛性焦虑症,接受rTMS治疗,情绪障碍持续显着改善,运动障碍进一步改善。
这一结果对使用rTMS治疗HD患者的MDD和舞蹈症提出了质疑,尤其是在课程的早期。
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