关键词: Immunotherapy allergic rhinitis antihistamines corticosteroids novel therapeutic modalities. pharmacotherapy

Mesh : Humans Rhinitis, Allergic / drug therapy Anti-Allergic Agents / therapeutic use Evidence-Based Medicine Quality of Life

来  源:   DOI:10.2174/0113816128295952240306072100

Abstract:
Allergic rhinitis (AR) is an IgE-mediated atopic disease that occurs due to inhaled antigens in the immediate phase. Misdiagnosis, insufficient treatment, or no treatment at all are frequent problems associated with the widespread condition known as chronic allergic rhinitis. AR symptoms include runny, itchy, stuffy, and sneezing noses. Asthma and nasal polyps, for example, sometimes occur simultaneously in patients. In order for people living with AR to be as comfortable and productive as possible, treatment should center on reducing their symptoms. The online sources and literature, such as Pubmed, ScienceDirect, and Medline, were reviewed to gather information regarding therapeutic modalities of AR and evidence-based treatments for the disease as the objectives of the present study. An increasing number of people are suffering from AR, resulting in a heavy financial and medical burden on healthcare systems around the world. Undertreating AR frequently results in a decline in quality of life. Treatment compliance is a critical challenge in the administration of AR. Innovative therapies are needed for RA to provide patients with symptom alleviation that is less expensive, more effective, and longer duration of action. Evidence-based guidelines are helpful for managing AR illness. Treating AR according to evidence-based standards can help in disease management. AR treatment includes allergen avoidance, drug therapy, immunotherapy, patient education, and follow-up. However, AR treatment with intranasal corticosteroids is more popular. Hence, in this review article, treatment options for AR are discussed in depth. We also discussed the incidence, causes, and new treatments for this clinical condition.
摘要:
过敏性鼻炎(AR)是一种IgE介导的特应性疾病,由于吸入抗原而在即刻阶段发生。误诊,治疗不足,或者根本没有治疗是与称为慢性过敏性鼻炎的广泛病症相关的常见问题。AR症状包括流鼻涕,发痒,闷,打喷嚏的鼻子。哮喘和鼻息肉,例如,有时同时发生在患者身上。为了让生活在AR中的人尽可能舒适和高效,治疗应以减轻症状为中心。在线资源和文献,如Pubmed,ScienceDirect,还有Medline,进行了审查,以收集有关AR的治疗方式和该疾病的循证治疗的信息,作为本研究的目标。越来越多的人患有AR,给世界各地的医疗系统带来沉重的财政和医疗负担。AR治疗不足经常导致生活质量下降。治疗依从性是AR管理中的关键挑战。RA需要创新的疗法来为患者提供更便宜的症状缓解,更有效,和更长的行动持续时间。循证指南有助于治疗AR疾病。根据循证标准治疗AR有助于疾病管理。AR治疗包括避免过敏原,药物治疗,免疫疗法,患者教育,和后续行动。然而,鼻内皮质类固醇的AR治疗更受欢迎。因此,在这篇评论文章中,对AR的治疗方案进行了深入的讨论。我们还讨论了发病率,原因,和这种临床疾病的新疗法。
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