PDF(Pubmed)
Abstract：
BACKGROUND: People with dementia and their caregivers are prone to suicidal behaviors due to difficulty adjusting to their initial caregiving role and due to emotional disturbances resulting from deterioration of functioning. The present systematic review (1) explored the prevalence of and risk factors for suicidal behavior and (2) assessed the similarities and differences in the prevalence and risk factors for suicidal behavior between people with dementia and their caregivers.
METHODS: A comprehensive literature search for research articles published between 1950 and 2023 was carried out using major databases, such as Google Scholar, Web of Science, PubMed, Scopus, PsycINFO, EMBASE, the Cochrane Library, and Medline.
RESULTS: A total of 40 research articles were selected for review. A total of 12 research articles revealed that the prevalence of suicidal behavior among caregivers ranged from 4.7% to 26%. However, the risk of suicidal behavior among people with dementia was inconsistent, as only 17 out of 28 selected studies reported the risk of suicidal behavior among people with dementia. The risk factors associated with suicidal behavior among caregivers of people with dementia could be both self-related and care receiver-related factors, whereas risk factors in people with dementia were self-related factors. Notably, greater cognitive decline, which impairs individuals\' ability to carry out complex acts and planning, may lower their suicidal risk. Finally, assessment of the risk of bias indicated that 95% of the selected studies had unclear risk.
CONCLUSIONS: Self-related and care receiver-related factors should be assessed among caregivers of people with dementia to evaluate the risk of suicidal behavior. In addition, we recommend evaluating suicidal risk in people with dementia in the early phase of dementia when cognitive decline is less severe. However, as the majority of the selected studies had unclear risk of bias, future studies with improved methodologies are warranted to confirm our study findings.
METHODS: A comprehensive literature search for research articles published between 1950 and 2023 was carried out using major databases, such as Google Scholar, Web of Science, PubMed, Scopus, PsycINFO, EMBASE, the Cochrane Library, and Medline.
RESULTS: A total of 40 research articles were selected for review. A total of 12 research articles revealed that the prevalence of suicidal behavior among caregivers ranged from 4.7% to 26%. However, the risk of suicidal behavior among people with dementia was inconsistent, as only 17 out of 28 selected studies reported the risk of suicidal behavior among people with dementia. The risk factors associated with suicidal behavior among caregivers of people with dementia could be both self-related and care receiver-related factors, whereas risk factors in people with dementia were self-related factors. Notably, greater cognitive decline, which impairs individuals\' ability to carry out complex acts and planning, may lower their suicidal risk. Finally, assessment of the risk of bias indicated that 95% of the selected studies had unclear risk.
CONCLUSIONS: Self-related and care receiver-related factors should be assessed among caregivers of people with dementia to evaluate the risk of suicidal behavior. In addition, we recommend evaluating suicidal risk in people with dementia in the early phase of dementia when cognitive decline is less severe. However, as the majority of the selected studies had unclear risk of bias, future studies with improved methodologies are warranted to confirm our study findings.
摘要：
背景：痴呆症患者及其照顾者由于难以适应其最初的照顾角色以及由于功能恶化导致的情绪障碍而倾向于自杀行为。本系统评价（1）探讨了自杀行为的患病率和危险因素，（2）评估了痴呆症患者及其照顾者之间自杀行为的患病率和危险因素的异同。
方法：使用主要数据库对1950年至2023年之间发表的研究文章进行了全面的文献检索，比如谷歌学者，WebofScience,PubMed,Scopus,PsycINFO,EMBASE,Cochrane图书馆,Medline
结果：共选择40篇研究文章进行综述。共有12篇研究文章显示，护理人员中自杀行为的患病率为4.7％至26％。然而,痴呆症患者自杀行为的风险不一致，因为28项选定研究中只有17项报告了痴呆症患者的自杀行为风险。与痴呆患者照顾者自杀行为相关的危险因素可能是自我相关因素和照顾者相关因素。而痴呆患者的危险因素是自身相关因素。值得注意的是,更大的认知能力下降，这削弱了个人执行复杂行为和计划的能力，可以降低自杀风险。最后,对偏倚风险的评估表明,95%的入选研究存在不明确的风险.
结论：应评估痴呆症患者照顾者的自我相关因素和照顾者相关因素，以评估自杀行为的风险。此外,我们建议在认知功能减退较不严重的痴呆早期评估痴呆患者的自杀风险.然而,由于大多数选定的研究都有不清楚的偏倚风险，有必要采用改进方法的未来研究来证实我们的研究结果.
方法：使用主要数据库对1950年至2023年之间发表的研究文章进行了全面的文献检索，比如谷歌学者，WebofScience,PubMed,Scopus,PsycINFO,EMBASE,Cochrane图书馆,Medline
结果：共选择40篇研究文章进行综述。共有12篇研究文章显示，护理人员中自杀行为的患病率为4.7％至26％。然而,痴呆症患者自杀行为的风险不一致，因为28项选定研究中只有17项报告了痴呆症患者的自杀行为风险。与痴呆患者照顾者自杀行为相关的危险因素可能是自我相关因素和照顾者相关因素。而痴呆患者的危险因素是自身相关因素。值得注意的是,更大的认知能力下降，这削弱了个人执行复杂行为和计划的能力，可以降低自杀风险。最后,对偏倚风险的评估表明,95%的入选研究存在不明确的风险.
结论：应评估痴呆症患者照顾者的自我相关因素和照顾者相关因素，以评估自杀行为的风险。此外,我们建议在认知功能减退较不严重的痴呆早期评估痴呆患者的自杀风险.然而,由于大多数选定的研究都有不清楚的偏倚风险，有必要采用改进方法的未来研究来证实我们的研究结果.
